PERITONEAL RESTING WITH HEPARINIZED LAVAGE REVERSES PERITONEAL TYPE I MEMBRANE FAILURE. A COMPARATIVE STUDY OF THE RESTING EFFECTS ON NORMAL MEMBRANES

摘要

Background: Ultrafiltration failure (UFF) is a serious complication of long-term peritoneal dialysis (PD). Peritoneal rest (PR) has been demonstrated as a valid treatment to reverse the functional changes that occur in UFF. The effects of PR on a normally functioning human peritoneum are unknown but are expected to be neutral. Our hypothesis was that PR positively modifies peritoneal function in patients with UFF, in contrast to the absence of effects when PR is applied under normal conditions.