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The Duke University scandal - What can be done?

机译:杜克大学丑闻-该怎么办?

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Purpose: To highlight the importance of establishing the reproducibility of findings of clinical research. Summary: Clinical research is often conducted to find solution to the prevailing problems related to a particular disease, such as cancer. Patients are subjected to clinical tests and the test results are analyzed before revealing the findings for practical use. At times such findings are reported as research outcomes and get published in leading research journals. In this article, it is discussed about the pros and cons of a research work published by a researcher of the Duke University. Though the work is claimed to be as a grand success, the same has been criticized by other researchers for its lack of reproducibility. Its statistical worthiness is also questioned. Terming this as the Duke University Scandal, suggestions are given for what can be done to overcome such problems. The lesions learned from the practice of the Duke University have revealed answers for many questions.
机译:目的:强调建立临床研究结果可重复性的重要性。简介:通常进行临床研究以找到解决与特定疾病(例如癌症)相关的普遍问题的方法。对患者进行临床测试,并对测试结果进行分析,然后再揭示出实际应用的结果。有时,这些发现被报告为研究成果,并被发表在领先的研究期刊上。本文讨论了杜克大学研究人员发表的一项研究工作的利弊。尽管这项工作被认为是巨大的成功,但由于缺乏可重复性,其他研究人员也批评该工作。其统计价值也受到质疑。这被称为杜克大学丑闻,提出了解决这些问题的建议。从杜克大学的实践中学到的病变揭示了许多问题的答案。

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