Risk for placental abruption following amniocentesis and chorionic villus sampling.

摘要

Amniocentesis and chorionic villus sampling during the first and second trimesters of pregnancy are widely used methods for prenatal diagnosis. Much interest has focused on the risks of miscarriages and fetal loss as well as fetal morbidity and maternal psychological impact of these invasive procedures (Cederholm and Axelsson, 1997; Cederholm et al., 1999; Cahill et al., 2009).Placental abruption complicates 0.38-1% of pregnancies and is the leading cause of vaginal bleeding in the second half of pregnancy (Nilsen et al., 2008). Approximately 10% of preterm births and even one third of all perinatal deaths are caused by placental abruption (Oyelese et al., 2006). Maternal deaths due to placental abruption are rare, but still, for example, in Finland the maternal mortality ratio (MMR) of placental abruption is seven times higher than the overall MMR (Tikkanen et al, 2009).