Full polysaccharide chitosan-CMC membrane and silver nanocomposite: synthesis, characterization, and antibacterial behaviors

摘要

Chitosan-carboxymethyl cellulose (CMC) full polysaccharide membrane was prepared by cross-linking of chitosan with CMC dialdehyde and subsequent reductive amination. CMC dialdehyde molecule was prepared by periodate oxidation of CMC and then applied as a cross-linking agent to form a new membrane network. The properties of oxidized CMC were investigated by various methods such as Fourier transform infrared (FT-IR) spectroscopy, H-1 NMR spectroscopy, and viscosity test. Then, novel chitosan-CMC silver nanocomposite was prepared using chitosan-CMC as a carrier. The structure of the chitosan-CMC membrane and the silver nanocomposite were confirmed by FT-IR spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and thermogravimetric analysis (TGA). TEM images indicate that the chitosan-CMC nanocomposite comprises silver nanoparticles with diameters in the range of about 5-20nm. The antibacterial studies of the nanocomposite were also evaluated. The chitosan-CMC silver nanocomposite demonstrates good antibacterial activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli. Copyright (c) 2016 John Wiley & Sons, Ltd.