The transcription factor Forkhead Box P3 gene variants affect idiopathic recurrent pregnancy loss

摘要

Introduction: Forkhead Box P3 (FOXP3) is an essential transcription factor for the induction and development of Tregs. It plays an important role in regulation and suppression of immune responses. We tested whether FOXP3 gene variants are associated with idiopathic recurrent miscarriages (IRM).