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ONCOLOGY - AN OVERVIEW

机译:肿瘤学-概述

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Cancer a malignant tumor is not such a disease as with single etiology, definite identifiable clinical features and established planned management with definite outcome. The etiology is diverse, some of which are known and many others are yet to be revealed. The clinical features may mimic benign tumors, metabolic and other disorders. The cancer risk has been found to be predominantly related to environmental factors which is about 65%. Heritable factors contribute about 26% to 42%. The tumor may remain localised for some period. But the most critical problem regarding character of cancer is its mode of unpredictable and uncertain spread (Metastasis) to distant places which may be revealed or occult and solitary or at multiple sites anywhere in the body. The spread is commonly by lymph or blood. Metastasis is the prime hindrance to assess the disease status. All these factors create unrest in the mind of clinician regarding plan of management and to foresee the outcome of treatment, and prognosis. The most hopeful part is that cancer risk from environmental factors is about 65% and that this risk can be drastically reduced adopting related preventive measures viz. change in food habit, life style, vulnerable occupations; total abstainment from addictions like smoking or smokeless tobacco use, alcohol; identification of heritable factors, high risk group and preneoplastic conditions. Now a days cancer is not out of reach. Many can be prevented, some can be cured and others can be provided better life style or at least a peaceful ultimate.
机译:恶性肿瘤不是一种病因单一,可明确确定的临床特征,已确定的计划治疗并具有明确结果的疾病。病因是多种多样的,其中一些是已知的,还有许多尚待揭示。临床特征可模仿良性肿瘤,代谢和其他疾病。已经发现癌症风险主要与约65%的环境因素有关。遗传因素贡献了大约26%至42%。肿瘤可能会保留一段时间。但是,关于癌症特征的最关键问题是其向远处的不可预测和不确定的扩散(转移)方式,这种方式可能被发现或隐匿或孤立,或在身体的任何部位出现。传播通常是通过淋巴或血液。转移是评估疾病状况的主要障碍。所有这些因素在临床医生的心中引起了管理计划的不安,并预见了治疗结果和预后。最有希望的部分是,来自环境因素的癌症风险约为65%,可以通过采取相关的预防措施来大幅降低这种风险。改变饮食习惯,生活方式,脆弱的职业;完全戒除吸烟或无烟烟草,酒精等成瘾;确定遗传因素,高危人群和肿瘤前状况。现在,癌症已不再遥不可及。许多可以预防,一些可以治愈,其他可以提供更好的生活方式,或者至少是和平的终极选择。

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