Patients with Plasma Cell Disorders Examined at Whole-Body Dynamic Contrast-enhanced MR Imaging: Initial Experience

摘要

This study was approved by the institutional review board, and informed consent was obtained from all subjects. The authors prospectively evaluated the feasibility of multistation whole-body dynamic contrast material–enhanced magnetic resonance (MR) imaging performed in patients with plasma cell disorders to assess disease extension and the time–signal intensity curves of diffuse and focal bone marrow infiltration. Three healthy adult male volunteers (age range, 29–31 years) and 21 patients (12 men, nine women; age range, 34–79 years) underwent whole-body dynamic unenhanced (volunteers) and contrast-enhanced MR imaging, which was performed by using an 18-channel 1.5-T MR system. A five-station (three sagittal and two coronal planes) fat-saturated three-dimensional gradient-echo sequence (3.3–3.6/1.3 [repetition time msec/echo time msec], 20° flip angle, voxel size of 2 × 2.6 × [3–5] mm) was performed seven times. The temporal resolution of the five-station dynamic contrast-enhanced examination was 60 seconds with use of parallel imaging. Time–signal intensity curves for the bone marrow and the focal lesions were successfully obtained in all patients. Supplemental material: http://radiology.rsnajnls.org/cgi/content/full/250/3/905/DC1 http://radiology.rsnajnls.org/cgi/content/full/250/3/905/DC2 http://radiology.rsnajnls.org/cgi/content/full/250/3/905/DC3 © RSNA, 2009