首页> 外国专利> pharmaceutical composition, lyophilized composition, process for manufacturing a pharmaceutical composition, methods for treating a cellular proliferative disorder in a patient and for imaging and detecting a cellular proliferative disorder in a patient, and, composition for detecting and imaging a cellular proliferative disorder. in a patient

pharmaceutical composition, lyophilized composition, process for manufacturing a pharmaceutical composition, methods for treating a cellular proliferative disorder in a patient and for imaging and detecting a cellular proliferative disorder in a patient, and, composition for detecting and imaging a cellular proliferative disorder. in a patient

机译:药物组合物,冻干的组合物,制备药物组合物的方法,用于治疗患者的细胞增生性疾病以及对患者的细胞增生性疾病进行成像和检测的方法,以及用于检测和成像细胞增生性疾病的组合物。在一个病人

摘要

1/1 summary â € œpharmaceutical composition, freeze-dried composition, process for making a pharmaceutical composition, methods for treating a cell proliferative disorder in a patient and for imaging and detecting a cell proliferative disorder in a patient , and, composition for detecting and imaging a cell proliferative disorder in a patient. Therapeutic prodrug compositions which can be delivered to a patient via an emulsion are provided herein. which comprises a peptide-linked therapeutic drug that is efficiently and specifically cleaved by a selected protease associated with a cell proliferative disorder, including cancer cells, for example, cancer cells. prostate, fan or breast in a patient. Also provided herein are methods of treating cellular proliferative disorders, including cancers, with the therapeutic prodrug compositions.
机译:1/1摘要–药物组合物,冻干组合物,药物组合物的制备方法,用于治疗患者细胞增殖性疾病以及对患者细胞成像和检测的方法,以及用于检测和治疗的组合物对患者的细胞增殖性疾病进行成像。本文提供了可以通过乳剂递送给患者的治疗性前药组合物。其包含肽连接的治疗药物,该药物被与细胞增殖性疾病(包括癌细胞,例如癌细胞)相关的所选蛋白酶有效和特异性地裂解。患者的前列腺,风扇或乳房。本文还提供了用治疗性前药组合物治疗细胞增殖性疾病,包括癌症的方法。

著录项

  • 公开/公告号BR112015008421A2

    专利类型

  • 公开/公告日2017-08-08

    原文格式PDF

  • 申请/专利权人 GENSPERA INC.;

    申请/专利号BR20151108421

  • 发明设计人 ANDREW X. CHEN;YALI TSAI;

    申请日2013-10-14

  • 分类号A61K38;A61P35;

  • 国家 BR

  • 入库时间 2022-08-21 13:40:14

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