Involvement of gamma-hydroxybutyrate (GHB) and GABA-B receptors in the acute behavioral effects of GHB in baboons

Amy K. Goodwin; Wolfgang Froestl; Elise M. Weerts

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Involvement of gamma-hydroxybutyrate (GHB) and GABA-B receptors in the acute behavioral effects of GHB in baboons

机译：γ-羟基丁酸酯（GHB）和GABA-B受体参与狒狒GHB的急性行为影响

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摘要

Gamma-hydroxybutyrate (GHB) is used for the treatment of narcolepsy, but it is also a drug of abuse. The behavioral pharmacology of GHB is not well defined.

机译：γ-羟基丁酸酯（GHB）用于治疗发作性睡病，但它也是一种滥用药物。 GHB的行为药理学尚不明确。

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来源
《Psychopharmacology》 |2005年第2期|342-351|共10页
作者
Amy K. Goodwin; Wolfgang Froestl; Elise M. Weerts;
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作者单位

Johns Hopkins Bayview Behavioral Biology Research Center;

Neuroscience Research Novartis Pharma AG;

Johns Hopkins Bayview Behavioral Biology Research Center;

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原文格式 PDF
正文语种 eng
中图分类
关键词
Xyrem; Reinforcement schedule; Operant behavior; Conditioned performance; Feeding; Ataxia;

机译：Xyrem;补强计划;操作行为;状况良好;进食;共济失调;

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1. Behavioral effects and pharmacokinetics of gamma-hydroxybutyrate (GHB) precursors gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD) in baboons. [J] . Goodwin AK, Brown PR, Jansen EE, Psychopharmacology . 2009,第3期

机译：狒狒中γ-羟基丁酸酯（GHB）前体γ-丁内酯（GBL）和1,4-丁二醇（1,4-BD）的行为效应和药代动力学。
2. Behavioral effects and pharmacokinetics of gamma-hydroxybutyrate (GHB) precursors gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD) in baboons [J] . A. K. Goodwin, P. R. Brown, E. E. W. Jansen, Psychopharmacology . 2009,第3期

机译：狒狒中γ-羟基丁酸酯（GHB）前体γ-丁内酯（GBL）和1,4-丁二醇（1,4-BD）的行为效应和药代动力学
3. Effects of gamma-Hydroxybutyrate (GHB) on Schedule-Controlled Responding in Rats:Role of GHB and GABA_B Receptors [J] . Lawrence P.Carter, Huifang Wu, Weibin Chen, The Journal of Pharmacology and Experimental Therapeutics: Official Publication of the American Society for Pharmacology and Experimental Therapeutics . 2004,第1期

机译：羟基丁酸（GHB）对大鼠日程控制反应的影响：GHB和GABA_B受体的作用
4. Mineralocorticoid and glucocorticoid receptors involvement in experimental thrombosis augmentation during acute aldosterone infusion in diabetic rats [C] . Szoka P., Gromotowicz-Poplawska A., Zakrzeska A., European Congress of Pharmacology . 2012

机译：矿物质激素和糖皮质激素受体参与在糖尿病大鼠急性醛固酮输注期间的实验血栓形成增强
5. Analysis of gamma-hydroxybutyrate (GHB) in beverages. [D] . Tschaekofske, Scott James. 2000

机译：饮料中γ-羟基丁酸酯（GHB）的分析。
6. Behavioral effects and pharmacokinetics of gamma-hydroxybutyrate (GHB) precursors gamma-butyrolactone (GBL) and 14-butanediol (14-BD) in baboons [O] . A. K. Goodwin, P. R. Brown, E. E. W. Jansen, -1

机译：狒狒中γ-羟基丁酸酯（GHB）前体γ-丁内酯（GBL）和14-丁二醇（14-BD）的行为效应和药代动力学
7. Gamma-hydroxybutyrate (GHB) and topiramate-clinically relevant drug interaction suggested by a case of coma and increased plasma GHB concentration [O] . Weiss, T, Müller, D, Marti, I, 2013

机译：昏迷和血浆GHB浓度升高提示存在γ-羟基丁酸酯（GHB）和托吡酯-临床相关药物相互作用

Involvement of gamma-hydroxybutyrate (GHB) and GABA-B receptors in the acute behavioral effects of GHB in baboons

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