机译:突变型SOD1二硫化物的氧化和聚集在家族性ALS发病机理中的作用
Department of Neuroscience, McKnight Brain Institute, University of Florida, Gainesville, FL 32610-0235;
Department of Neuroscience, McKnight Brain Institute, University of Florida, Gainesville, FL 32610-0235;
Department of Biochemistry and the X-ray Crystallography Core Laboratory, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900;
Department of Biochemistry and the X-ray Crystallography Core Laboratory, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900 Geriatric Research, Education, and Clinical Center, Department of Veterans Affairs, South Texas Veterans Health Care System, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900;
Department of Neuroscience, McKnight Brain Institute, University of Florida, Gainesville, FL 32610-0235;
neurodegenerative disease; protein misfolding;
机译:一个亚基间二硫键防止与家族性肌萎缩性侧索硬化症相关的超氧化物歧化酶-1突变体的体外聚集。
机译:共表达的野生SOD1蛋白对突变型Cu / Zn超氧化物歧化酶(SOD1)蛋白的稳定作用可加速家族性肌萎缩性侧索硬化小鼠的疾病进展。
机译:S-亚硝化蛋白二硫键异构酶对肌萎缩性侧索硬化症中突变型SOD1聚集和神经元细胞死亡的潜在影响。
机译:MARDI-TOF MS和FT-ICR MS的家族性肌萎缩外硬化相关交联Cu,Zn超氧化物歧化酶(SOD1)的分析
机译:芳硫基吡唑啉酮可阻止突变型SOD1聚集,并可能在肌萎缩性侧索硬化症的治疗中应用。
机译:突变型SOD1二硫化物的氧化和聚集在家族性ALS发病机理中的作用
机译:突变型SOD1二硫化物的氧化和聚集在家族性ALS发病机理中的作用