The influence of glutathione on the photochemical stability of collagen

摘要

The photochemical stability of collagen type I from young albino rat tail tendon in the presence of glutathione (GSH) was investigated using viscosimetry, UV-Vis spectrophotometry and spectrofluorimetry. The results suggest that glutathione makes collagen less resistant to the photolytic action of UV radiation. However, this antioxidant can protect the protein from UV photo- oxidation and the protection effect depends on its concentration in the protein solution.