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Glutamine prevents intestinal mucosal injury induced by cyclophosphamide in rats

机译:谷氨酰胺预防环磷酰胺诱导的大鼠肠粘膜损伤

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摘要

High doses of anticancer drugs often damage the intestinal mucosa. The purpose of the present study was to examine the effect of glutamine on mucosal damage induced by cyclophosphamide in a rat model, and to elucidate the mechanisms responsible for its protective effects.
机译:高剂量的抗癌药通常会损害肠粘膜。本研究的目的是在大鼠模型中检测谷氨酰胺对环磷酰胺诱导的粘膜损伤的作用,并阐明其保护作用的机制。

著录项

  • 来源
    《Pediatric Surgery International》 |2012年第3期|p.299-303|共5页
  • 作者单位

    Department of Surgery, Division of Pediatric Surgery, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan;

    Department of Surgery, Division of Pediatric Surgery, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan;

    Department of Surgery, Division of Pediatric Surgery, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan;

    Department of Surgery, Division of Pediatric Surgery, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan;

    Department of Surgery, Division of Pediatric Surgery, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Chemotherapy; Intestine; Glutamine; Glutathione; Apoptosis;

    机译:化学疗法;肠;谷氨酰胺;谷胱甘肽;细胞凋亡;

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