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Effect of alpha-naphthylisothiocyanate-induced liver injury on intestinal adaptation in a rat model of short bowel syndrome

机译:α-萘基异硫氰酸酯诱导的肝损伤对短肠综合征大鼠模型肠道适应的影响

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摘要

Progressive hyperbilirubinemia and end-stage liver failure are among the most serious complications of short bowel syndrome (SBS), representing the principle cause of death in a majority of fatal cases. In the current study, we examined the effects of alpha-naphthylisothiocyanate (ANIT)-induced liver injury on intestinal adaptation in a rat model of SBS.
机译:进行性高胆红素血症和终末期肝功能衰竭是短肠综合征(SBS)最严重的并发症,是大多数致命病例中主要的死亡原因。在当前的研究中,我们检查了SBS大鼠模型中α-萘基异硫氰酸酯(ANIT)诱导的肝损伤对肠道适应的影响。

著录项

  • 来源
    《Pediatric Surgery International》 |2012年第2期|p.161-169|共9页
  • 作者单位

    Laboratory of Intestinal Adaptation and Recovery, The Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel;

    Laboratory of Intestinal Adaptation and Recovery, The Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel;

    Laboratory of Intestinal Adaptation and Recovery, The Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel;

    Laboratory of Intestinal Adaptation and Recovery, The Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel;

    Dept of Pathology, Bnai Zion Medical Center, Haifa, Israel;

    Dept of Pediatric Surgery, Bnai Zion Medical Center, 47 Golomb St, P.O.B. 4940, 31048, Haifa, Israel;

    Department of Surgery, The Lucile Packard Children’s Hospital, Stanford University School of Medicine, Stanford, CA, USA;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Short bowel syndrome; Intestinal adaptation; α-Naphtylisocyocyanate; Liver; Rat;

    机译:短肠综合征;肠道适应;α-萘硫氰酸盐;肝;大鼠;

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