Palladium-catalyzed synthesis of 2-(aminomethyl)indoles from ethyl 3-(o-trifluoroacetamidophenyl)-1-propargyl carbonate

Ambrogio I; Cacchi S; Fabrizi G

首页> 外文期刊>Organic letters >Palladium-catalyzed synthesis of 2-(aminomethyl)indoles from ethyl 3-(o-trifluoroacetamidophenyl)-1-propargyl carbonate

【24h】

Palladium-catalyzed synthesis of 2-(aminomethyl)indoles from ethyl 3-(o-trifluoroacetamidophenyl)-1-propargyl carbonate

机译：钯催化3-（邻三氟乙酰氨基苯基）-1-炔丙基碳酸乙酯催化合成2-（氨基甲基）吲哚

获取原文

获取原文并翻译 | 示例

获取外文期刊封面封底 >>

开具论文收录证明 >>

文献代查 >>

团队文献服务 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The palladium-catalyzed reaction of ethyl 3-(o-trifluoroacetamidophenyl)-1-propargyl carbonate with piperazines in the presence of Pd(PPh3)(4) in THF at 80 degrees C affords 2-(piperazin-1-ylmethyl)indoles in excellent yields. Good to excellent yields are also obtained with other secondary amines.

机译：在Pd（PPh3）（4）在THF中，80°C下钯3-催化碳酸3-（邻三氟乙酰胺基苯基）-1-炔丙基碳酸酯与哌嗪的反应得到2-（哌嗪-1-基甲基）吲哚优异的产量。用其他仲胺也能获得良好至优异的产率。

著录项

来源
《Organic letters 》 |2006年第10期| p. 2083-2086| 共4页
作者
Ambrogio I; Cacchi S; Fabrizi G;
展开▼
作者单位

Univ Roma La Sapienza, Dipartimento Studi Chim & Tecnol Sostanze Biol Ca, I-00185 Rome, Italy;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类有机化学 ;
关键词
AMINOPALLADATION-REDUCTIVE ELIMINATION; RECEPTOR PARTIAL AGONISTS; ETA(3)-PROPARGYLPALLADIUM COMPLEXES; O-ALKYNYLTRIFLUOROACETANILIDES; PROPARGYLIC CARBONATES; PHASE SYNTHESIS; IONIC LIQUIDS; HYDROARYLATION; HYDROVINYLATION; DERIVATIVES;

机译：消除氨氧化-还原;受体部分激动剂;ETA（3）-炔丙基钯络合物;邻炔基三氟乙酰胺;炔基碳酸盐;相合成;离子液体;加氢芳基化;加氢乙烯基;

相似文献

外文文献
中文文献
专利

1. Palladium-catalyzed synthesis of 2-(aminomethyl)indoles from ethyl 3-(o-trifluoroacetamidophenyl)-1-propargyl carbonate [J] . Ambrogio I, Cacchi S, Fabrizi G Organic letters . 2006 ,第10期

机译：钯催化碳酸3-（邻三氟乙酰氨基苯基）-1-炔丙基碳酸乙酯合成2-（氨基甲基）吲哚
2. 2-Alkylindoles via palladium-catalyzed reductive cyclization of ethyl 3-(o-trifluoroacetamidophenyl)-1-propargyl carbonates [J] . Ilaria Ambrogio, Sandro Cacchi, Giancarlo Fabrizi Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry . 2007 ,第43期

机译：2-炔基吲哚通过钯催化3-（邻三氟乙酰氨基苯基）-1-炔丙基碳酸乙酯的还原环化
3. Palladium-Catalyzed Synthesis of 2-(Aminomethyl)indoles from 3-(o-Trifluoroacetamidoaryl)-1-propargylic Alcohols and Amines [J] . Sandro Cacchi, Giancarlo Fabrizi, Antonella Goggiamani, The Journal of Organic Chemistry . 2014 ,第1期

机译：钯 - 催化合成3-（o-三氟甲酰氨基甲酰甲基氨基甲基）-1-丙基醇和胺的2-（氨基甲基）吲哚
4. Synthesis of copper complexes of poly 2-(dimethylamino ethyl methacrylate)-b-poly (oligo (ethylene glycol) monomethylether methacrylate-b-poly 2-(dimethylamino ethyl methacrylate) [C] . Qianqian You, Puyu Zhang International Conference on Materials Science and Engineering . 2013

机译：聚2-（二甲基氨基甲基丙烯酸甲酯）-B-聚（寡烷基乙基乙基）单甲基醚甲基丙烯酸酯-B-聚2-（二甲基氨基甲基丙烯酸二甲基氨基乙酯）的铜复合物
5. Spectroscopic studies on carborane derivatives: Synthesis and characterization of partial cage degradation reactions of 1,2-(hydroxymethyl radical)-closo-carborane with 2-(aminomethyl)-pyridine. [D] . Gilbes, Blanca Janet. 2006

机译：碳硼烷衍生物的光谱研究：1,2-（羟甲基自由基）-氯甲烷与2-（氨基甲基）-吡啶的部分笼降解反应的合成和表征。
6. Synthesis of 2-(5-Nitropyrid-2-yl)-3-(4-substitutedphenyl)amino-isoxazol-5(2H)-ones and Their Rearrangements to Imidazo12-a- pyridines and Indoles with Triethylamine [O] . J. Khalafy, D. Setamdideh, K. Akbari Dilmaghani 2002

机译：2-（5-亚硝基吡啶-2-基）-3-（4-取代苯基）氨基-异恶唑-5（2H）-的合成及其与三乙胺的咪唑并12-a-吡啶和吲哚重排
7. Palladium-Catalyzed Synthesis of 2-(Aminomethyl)indoles from Ethyl 3-(o-Trifluoroacetamidophenyl)-1-propargyl Carbonate [O] . -1

机译：钯催化合成来自乙基3-（o-三氟乙酰苯基苯基）-1-丙基丙氨酸乙基乙基乙基乙基乙酯的合成2-（氨基甲基）吲哚
8. Results of a Local Lymph Node Assay in Mice (LLNA/IMDS) with 2-Propenoic Acid, 2-((((3-(Methylthio) Phenyl) Amino)Carbonyl)Oxy) Ethyl Ester. [R] . 2013

机译：用2-丙烯酸，2 - （（（（（3-（甲硫基）苯基）氨基）羰基）氧基）乙基酯在小鼠（LLNa / ImDs）中进行局部淋巴结测定的结果。

Palladium-catalyzed synthesis of 2-(aminomethyl)indoles from ethyl 3-(o-trifluoroacetamidophenyl)-1-propargyl carbonate

摘要

著录项

相似文献

相关主题

期刊订阅