Synthesis of Benzannulated N-Heterocycles by a Palladium-Catalyzed C-C/C-N Coupling of Bromoalkylamines

摘要

A palladium-catalyzed domino intermolecular alkylation/intramolecular amination of functionalized aryl iodides represents a new strategy for the synthesis of benzannulated N-heterocycles, affording functionalized indolines and tetrahydroquinolines from simple precursors.