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A novel estimation method of water-equivalent thicknesses of secondary particle tracks using secondary electron bremsstrahlung emitted from therapeutic ion beams for attenuation correction

机译:利用治疗离子束发射的二次电子致辐射进行衰减校正的二次粒子迹线水当量厚度的新估算方法

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Monitoring methods of therapeutic beams based on the measurement of secondary particles have been proposed and studied worldwide. Since secondary particles are influenced by substances in the human body before they reach detectors, estimation methods of the water-equivalent thickness of the tracks of the secondary particles are required for attenuation correction. In this work, we studied a novel estimation method of the water-equivalent thickness based on the observation of energy distribution of secondary electron bremsstrahlung (SEB) emitted from the trajectories of the therapeutic beams by Monte Carlo simulations. A ~(12)C-ion beam with an energy of 290 MeV/u was injected into a water phantom. The phantom was surrounded by a collimator having a CdTe detector behind the collimator. A distribution of energy deposition due to SEB emission was recorded during beam injection. The simulation was iterated by varying the radius of the phantom. The simulation results were plotted as an R_1 vs. R_2 scatter plot, where R_1 was defined as the ratio of the yield having a deposition energy between 30 and 40 keV to that between 20 and 30 keV, and R_2 was defined as the ratio of the yield having a deposition energy between 60 and 70 keV to that between 20 and 30 keV. We found that clusters are formed at different positions on the scatter plot by different radii of the phantom and that the water-equivalent thickness of the secondary particle tracks could be estimated using the R_1 vs. R_2 plot.
机译:在世界范围内已经提出并研究了基于二次粒子的测量的治疗束的监测方法。由于次级粒子在到达检测器之前会受到人体中物质的影响,因此需要进行次级粒子轨迹的水当量厚度的估计方法以进行衰减校正。在这项工作中,我们基于Monte Carlo模拟从治疗束轨迹发射的二次电子致辐射(SEB)的能量分布的观察结果,研究了一种新的水当量厚度估算方法。将能量为290 MeV / u的〜(12)C离子束注入到水模中。幻影被准直仪包围,准直仪在准直仪后方具有CdTe检测器。在束注入期间记录由于SEB发射引起的能量沉积的分布。通过更改体模的半径来重复进行仿真。模拟结果绘制为R_1与R_2的散点图,其中R_1定义为具有30到40 keV的沉积能量的产率与20到30 keV的沉积能量的比率,R_2定义为沉积能量的比率。沉积能量在60至70 keV之间至20至30 keV之间。我们发现,通过幻影的不同半径,在散布图上的不同位置形成了簇,并且可以使用R_1对R_2图来估算次粒子轨道的水当量厚度。

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