Man or mouse?

摘要

"We have moved away from studying human disease in humans," said Elias Zerhouni, the former director of the US National Institutes of Health, in 2013. The ability to knock out or insert specific genes in lab animals -miceinparticular-hasled ever more researchers to shift focus away from people. "The problem is that it hasn't worked, and it's time we stopped dancing around the problem… We need to refocus and adapt new methodologies for use in humans to understand disease biology in humans."