机译:阿尔茨海默氏病患者的T细胞反应性增加和CD8 + sup>记忆T细胞水平升高,以及阿尔茨海默氏病小鼠模型中的T细胞hypoactivity,对免疫疗法的影响
Institute of Pharmacology Biocenter building N260 Johann Wolfgang-Goethe-University Max-von-Laue-Strasse 9 60438 Frankfurt am Main Germany;
Institute of Pharmacology Biocenter building N260 Johann Wolfgang-Goethe-University Max-von-Laue-Strasse 9 60438 Frankfurt am Main Germany;
Department of Psychiatry and Psychotherapy I Johann Wolfgang-Goethe-University Heinrich-Hoffmann-Strasse 10 60528 Frankfurt am Main Germany;
Department of Psychiatry and Psychotherapy I Johann Wolfgang-Goethe-University Heinrich-Hoffmann-Strasse 10 60528 Frankfurt am Main Germany;
Department of Psychiatry and Psychotherapy I Johann Wolfgang-Goethe-University Heinrich-Hoffmann-Strasse 10 60528 Frankfurt am Main Germany;
Department of Psychiatry and Psychotherapy I Johann Wolfgang-Goethe-University Heinrich-Hoffmann-Strasse 10 60528 Frankfurt am Main Germany;
Department of Psychiatry and Psychotherapy I Johann Wolfgang-Goethe-University Heinrich-Hoffmann-Strasse 10 60528 Frankfurt am Main Germany;
Department of Psychiatry and Psychotherapy I Johann Wolfgang-Goethe-University Heinrich-Hoffmann-Strasse 10 60528 Frankfurt am Main Germany;
Institute of Pharmacology Biocenter building N260 Johann Wolfgang-Goethe-University Max-von-Laue-Strasse 9 60438 Frankfurt am Main Germany;
Neurodegeneration; CD3; Activation-induced cell death (AICD); CD69; BrdU; 4G10; Apoliporotein E (ApoE); Neuroinflammation; Hyposensitive; Neural–immune interaction;
机译:CD8 + sup>记忆性T细胞膨胀会导致幼稚T细胞免疫受损的CD4 + sup> T细胞依赖性CD8 + sup> T细胞免疫无能
机译:在过继性T细胞抗肿瘤免疫疗法中,将CD8 + T效应子建模为记忆过渡。
机译:长期抗逆转录病毒疗法可恢复结肠中CD8 + / CD161 ++粘膜相关的不变T细胞水平,并与CD8 + T细胞免疫激活相关
机译:IL-15转表达在记忆CD8 + T细胞反应中的作用。
机译:CD8 +记忆性T细胞膨胀可通过幼稚的T细胞无反应性削弱受损的CD4 + T细胞依赖性CD8 + T细胞免疫力
机译:CD8 + sup>内存T细胞膨胀使得通过Naïvet细胞anergy损害CD4 + sup> T细胞依赖性CD8 + sup> T细胞免疫力