Impact of [F-18]-fluoro-ethyl-tyrosine PET imaging on target definition for radiation therapy of high-grade glioma

af Rosenschold Per Munck; Costa Junia; Engelholm Svend Aage; Lundemann Michael J.; Law Ian; Ohlhues Lars; Engelholm Silke

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Impact of [F-18]-fluoro-ethyl-tyrosine PET imaging on target definition for radiation therapy of high-grade glioma

机译：[F-18]-氟乙基酪氨酸PET成像对高级胶质瘤放射治疗目标定义的影响

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Background. We sought to assess the impact of amino-acid F-18-fluoro-ethyl-tyrosine (FET) positron emission tomography (PET) on the volumetric target definition for radiation therapy of high-grade glioma versus the current standard using MRI alone. Specifically, we investigated the influence of tumor grade, MR-defined tumor volume, and the extent of surgical resection on PET positivity.

机译：背景。我们试图评估氨基酸F-18-氟代乙基酪氨酸（FET）正电子发射断层显像（PET）对高级神经胶质瘤放射治疗相对于目前仅使用MRI标准的体积目标定义的影响。具体而言，我们调查了肿瘤等级，MR定义的肿瘤体积以及手术切除程度对PET阳性的影响。

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来源
《Neuro-Oncology》 |2015年第5期|757-763|共7页
作者
af Rosenschold Per Munck; Costa Junia; Engelholm Svend Aage; Lundemann Michael J.; Law Ian; Ohlhues Lars; Engelholm Silke;
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作者单位

Rigshosp, Dept Oncol, Sect Radiotherapy, DK-2100 Copenhagen, Denmark|Univ Copenhagen, Niels Bohr Inst, DK-2100 Copenhagen, Denmark;

Rigshosp, Dept Oncol, Sect Radiotherapy, DK-2100 Copenhagen, Denmark|Rigshosp, Dept Clin Physiol Nucl Med & PET, DK-2100 Copenhagen, Denmark;

Rigshosp, Dept Oncol, Sect Radiotherapy, DK-2100 Copenhagen, Denmark;

Rigshosp, Dept Oncol, Sect Radiotherapy, DK-2100 Copenhagen, Denmark|Univ Copenhagen, Niels Bohr Inst, DK-2100 Copenhagen, Denmark;

Rigshosp, Dept Clin Physiol Nucl Med & PET, DK-2100 Copenhagen, Denmark;

Rigshosp, Dept Oncol, Sect Radiotherapy, DK-2100 Copenhagen, Denmark;

Skane Univ Hosp, Sect Radiat Oncol, Lund, Sweden;

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正文语种 eng
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FET-PET; glioma; MRI; radiation therapy; target definition;

机译：FET-PET;神经胶质瘤;MRI;放射治疗;目标定义;

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专利

1. Prognostic Significance of the minimal Time to Peak of the (F-18)-FET Tracer Recording of dynamic PET before Re-irradiation of Patients with high-grade Gliomas [J] . Fleischmann D. F., Unterrainer M., Bartenstein P., Strahlentherapie und Onkologie . 2016,第Suppla1期

机译：在重新照射高级胶质瘤患者之前，在（F-18） - （F-18）-FET示踪剂记录中的峰值峰值峰值的预后意义
2. Dosimetric impact of amino acid positron emission tomography imaging for target delineation in radiation treatment planning for high-grade gliomas [J] . Tomas Kazda, Deanna H. Pafundi, Alan Kraling, Physics and Imaging in Radiation Oncology . 2018,第2期

机译：氨基酸正电子发射断层扫描成像对高级神经胶质瘤放射治疗计划中靶标勾画的剂量学影响
3. Prostate-Specific Membrane Antigen-Targeted Imaging With [F-18] DCFPyL in High-Grade Gliomas [J] . Fragomeni Roberto Andres Salas, Menke Joshua R., Holdhoff Matthias, Clinical nuclear medicine . 2017,第10期

机译：前列腺特异性膜抗原靶向成像与高级胶质瘤中的[F-18] DCFPYL
4. Concurrent Thermochemoradiotherapy for Brain High-Grade Glioma [C] . A. I. Ryabova, V. A. Novikov, E. L. Choinzonov, International Conference on Physics of Cancer . 2016

机译：脑高等胶质瘤的同时热化学疗法
5. Gene therapy and radiation of malignant glioma by targeting glioma specific lactate transporter. [D] . Colen, Chaim B. 2005

机译：靶向神经胶质瘤特异性乳酸转运蛋白的基因治疗和恶性神经胶质瘤的放射。
6. Impact of 18F-fluoro-ethyl-tyrosine PET imaging on target definition for radiation therapy of high-grade glioma [O] . Per Munck af Rosenschold, Junia Costa, Svend Aage Engelholm, 2015

机译：18F-氟乙基酪氨酸PET成像对高级神经胶质瘤放射治疗目标定义的影响
7. Somatostatin receptor subtype 2 in high-grade gliomas: PET/CT with Ga-DOTA-peptides, correlation to prognostic markers, and implications for targeted radiotherapy [O] . 2015

机译：高级神经胶质瘤中生长抑素受体亚型2：具有Ga-DOTA肽的PET / CT，与预后标志物的相关性以及对靶向放射治疗的意义

Impact of [F-18]-fluoro-ethyl-tyrosine PET imaging on target definition for radiation therapy of high-grade glioma

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