CD4+CD25+ T-cell populations expressing CD134 and GITR are associated with disease activity in patients with Wegener's granulomatosis

Benjamin Wilde1 Sebastian Dolff1 Xin Cai1 Christof Specker2 Jan Becker3 Martin Tötsch3 Ulrich Costabel4 Jan Dürig5 Andreas Kribben1 Jan Willem Cohen Tervaert6 Kurt Werner Schmid3 and Oliver Witzke1

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CD4+CD25+ T-cell populations expressing CD134 and GITR are associated with disease activity in patients with Wegener's granulomatosis

机译：韦格纳肉芽肿病患者表达CD134和GITR的CD4 + CD25 + T细胞群体与疾病活动相关

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Background. An increased CD4+ CD25+ T-cell population is observed in Wegener's granulomatosis (WG). This T-cell population is not well characterized yet and their contribution to the disease pathogenesis remains obscure.

机译：背景。在韦格纳肉芽肿病（WG）中观察到CD4 + CD25 + T细胞数量增加。该T细胞群体的特征尚不明确，它们对疾病发病机理的贡献仍然不清楚。

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《Nephrology Dialysis Transplantation》 |2009年第1期|p.161-171|共11页
作者
Benjamin Wilde1 Sebastian Dolff1 Xin Cai1 Christof Specker2 Jan Becker3 Martin Tötsch3 Ulrich Costabel4 Jan Dürig5 Andreas Kribben1 Jan Willem Cohen Tervaert6 Kurt Werner Schmid3 and Oliver Witzke1;
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1Department of Nephrology, University Duisburg-Essen 2Department of Rheumatology and Clinical Immunology, Kliniken Essen Süd 3Institute of Pathology and Neuropathology, University Duisburg-Essen 4Department of Pneumology/Allergy, Ruhrlandklinik Essen 5Department of Hematology, University Duisburg-Essen, Germany 6Department of Internal Medicine, Division of Clinical and Experimental Immunology, University Hospital Maastricht, The Netherlands;

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1. CD4+CD25+ T-cell populations expressing CD134 and GITR are associated with disease activity in patients with Wegener's granulomatosis. [J] . Wilde B, Dolff S, Cai X, Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Association - European Renal Association . 2009,第1期

机译：表达CD134和GITR的CD4 + CD25 + T细胞群体与韦格纳肉芽肿病患者的疾病活动相关。
2. Expanded T cell populations in patients with Wegener's granulomatosis: characteristics and correlates with disease activity. [J] . Giscombe R, Nityanand S, Lewin N, Journal of Clinical Immunology . 1998,第6期

机译：韦格纳肉芽肿病患者的T细胞数量增加：特征并与疾病活动相关。
3. Expanded T cell populations in patients with Wegener's granulomatosis: characteristics and correlates with disease activity. [J] . Giscombe R, Nityanand S, Lewin N, Journal of Clinical Immunology . 1998,第6期

机译：韦格纳肉芽肿病患者的T细胞数量增加：特征并与疾病活动相关。
4. Expression of CD4+CD25+ T regulatory cells and Foxp3 in peripheral blood of patients with Rheumatoid Arthritis Patient [C] . Kexin Sun, Yan Li, Suhong Guo, International Conference on Applied Science, Engineering and Technology . 2013

机译：类风湿性关节炎患者外周血CD4 + CD25 + T调节细胞和FOXP3的表达
5. Mathematical Models of T-Cell Population Dynamics in Aging and Immune Disease [D] . Lewkiewicz, Stephanie Marissa. 2018

机译：衰老和免疫疾病中T细胞群体动力学的数学模型
6. Interference of PR3-ANCA with the enzymatic activity of PR3: differences in patients during active disease or remission of Wegeners granulomatosis [O] . Y M Van Der Geld, A T J Tool, J Videler, 2002

机译：PR3-ANCA对PR3酶活性的干扰：活动性疾病或韦格纳肉芽肿病缓解期间患者的差异
7. CD4+CD25+ T-cell populations expressing CD134 and GITR are associated with disease activity in patients with Wegener's granulomatosis [O] . B. Wilde, S. Dolff, X. Cai, 2008

机译：表达CD134和GITR的CD4 + CD25 + T细胞群与Wegener肉芽肿病患者的疾病活动相关

CD4+CD25+ T-cell populations expressing CD134 and GITR are associated with disease activity in patients with Wegener's granulomatosis

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