Neuron protection agency

摘要

On page 805 of this issue, Arrasate and colleagues show that clumps of mutant protein, seen in certain neurons and characteristic of Huntington's disease, reduce the chance that the neurons will die — at least in culture. So, why is this worth noting? The answers lie in the ingenious manner in which the investigators made their observations, and because they address a point of fervent debate among those studying many human neuro-degenerative diseases, including Hunting-ton's disease.