THIS ISSUE

摘要

The hype that greeted the development of systems biology was followed by inevitable disappointment. But in reality, much groundwork has been done and tangible progress is expected. In a Commentary this week, Adriano Henney and Giulio Superti-Furga broaden a debate that began at a recent workshop in Portofino, Italy, on the application of systems biology to drug discovery by inviting Nature readers to contribute their ideas. Portofino delegates drew up 'roadmaps' for three areas - metabolic disorders, cancer, and inflammation and infectious diseases - and are developing them as live documents to monitor progress.