In Vitro Characterization of the Enzymes Involved in TDP-D-Forosamine Biosynthesis in the Spinosyn Pathway of Saccharopolyspora spinosa

摘要

Forosamine (4-dimethylamino)-2,3,4,6-tetradeoxy-β-d-threo-hexopyranose) is a highly deoxy-genated sugar component of several important natural products, including the potent yet environmentally benign insecticide spinosyns. To study D-forosamine biosynthe