A C_10 chiron applicable to the synthesis of archaebacterial lipids

摘要

The membrane lipids of archaebacteria may be an important factor in the unusual adaptation of such organisms to extremes of temperature, salt concentration, and pH. Among the most common lipids isolated from these prokaryotes are derivatives of two C_2-symmetric, sn-2,3-bisbiphytanylglycerol tetraethers 1 and 2 (R, R' =glycoside, phosphate ester, hexitol, etc.), containing a 72-membered ring with 16 configurationally defined metyl groups Chart 1).