Analogue Compounds Of Archaebacterial Membrane Lipids And Liposomal Compounds Integrating Such Compounds

摘要

The invention relates to a compound of general formula (I): where =0 or 1, Z=O, S or CH_1-2, R₁ and R₂ independently=OH or OY, where Y=a protecting group, OR₃, where R₃=a monosaccharide or disaccharide group, A₁-CH₂—N⁺(CH₃)₃, X⁻, where X=halogen, A₁=an amide (NHC(O)) or ester (OC(O)) bond, OPO(OM)₂, where M=an alkali or alkali earth metal, OP(O)O⁻—O(CH₂)₂—N⁺(CH₃)₃, A₂-(PEG_X1-A₃)_n-R₄, where n=0 or 1, PEG_x1=a polyethyleneglycol of molecular weight X₁, where X₁, ??5,000 daltons, A₂ and A₃ independently=a ether (O), ester (OC(O)), amide (NHC((O)), urea (NHC(O)NH), thiourea (NHC(S)NH), or thioether (S) bond and R₄=a directing agent.;