A carbohydrate-based approach for the total synthesis of 1,3-polyol/alpha-pyrone antifungal natural products

Ramana CV; Srinivas B; Puranik VG; Gurjar MK

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A carbohydrate-based approach for the total synthesis of 1,3-polyol/alpha-pyrone antifungal natural products

机译：一种基于碳水化合物的方法，用于全合成1,3-多元醇/α-吡喃酮抗真菌天然产物

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摘要

An elimination and stereoselective hydrogenation of alpha-D-glucoheptonic-gamma-lactone derivative has been applied to prepare a differentially protected anti,anti-1,3,5-triol system, the utility of which has been extended for the total synthesis of anti-fungal 1,3-polyol/alpha-pyrone natural products.

机译：消除和立体选择性氢化α-D-葡庚酮-γ-内酯衍生物已用于制备差异保护的抗，抗-1,3,5-三醇体系，其实用性已扩展到抗-真菌1,3-多元醇/α-吡喃酮天然产物。

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来源
《The Journal of Organic Chemistry》 |2005年第20期|p. 8216-8219|共4页
作者
Ramana CV; Srinivas B; Puranik VG; Gurjar MK;
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作者单位

Natl Chem Lab, Pune 411008, Maharashtra, India;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类有机化学;
关键词
CRYPTOCARYA-STRICTIFOLIA; ABSOLUTE-CONFIGURATION; ASYMMETRIC-SYNTHESIS; PASSIFLORICIN-A; ALPHA-PYRONES; (+)-STRICTIFOLIONE; DIACETATE; LACTONE; ESTERS;

机译：隐球菌;绝对构型;不对称合成;PASSIFLORICIN-A;α-吡咯烷酮;（+）-STRIPIFOLIONE;双乙酸酯;内酯;酯;

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1. Syntheses of natural 1,3-polyol/alpha-pyrone and its all stereoisomers to estimate antifungal activities against plant pathogenic fungi [J] . Yamauchi Satoshi, Isozaki Yasuyoshi, Nishiwaki Hisashi, Bioorganic and Medicinal Chemistry Letters . 2015,第10期

机译：合成天然1,3-多元醇/α-吡喃酮及其所有立体异构体，以评估其对植物病原真菌的抗真菌活性
2. Formal Synthesis of Natural 1,3-Polyol/alpha-Pyrone Diastereoisomers [J] . Sabitha G, Gopal P, Yadav JS Helvetica chimica acta . 2008,第12期

机译：天然1,3-多元醇/α-吡咯非对映异构体的形式合成
3. Carbohydrate-based routes to salicylate natural products: formal total synthesis of (+)-apicularen A from D-glucal [J] . Arwel Lewis, Ian Stefanuti, Simon A.Swain, Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry . 2001,第32期

机译：基于碳水化合物的水杨酸天然产物途径：由D-葡萄糖醛正式合成（+）-apicularen A
4. CARBOHYDRATE-BASED 1,3-OXAZOLINE-2-THIONES: FROM SYNTHESIS TO BIOLOGICAL APPLICATIONS [C] . Castilla J., Cruz D., Risquez Cuadro R. International Carbohydrate Symposium . 2013

机译：基于碳水化合物的1,3-恶唑啉-2-脚：从合成到生物应用
5. Diastereoselective strategies for the synthesis of glutamate-containing natural products: Total synthesis of (S)-(+)-lycoperdic acid and studies toward the total synthesis of (-)-dysiherbaine and the design and synthesis of a scaffold for glutamate receptor ligands using a natural product-based library approach. [D] . Cohen, Jamie Lisa. 2006

机译：合成含谷氨酸天然产物的非对映选择性策略：（S）-（+）-乙二酸的全合成，以及对（-）-dysiherbaine的全合成以及使用谷氨酸受体配体的支架设计和合成的研究基于自然产品的图书馆方法。
6. Natural Product Synthesis Special Feature: A unified approach to polyene macrolides: Synthesis of candidin and nystatin polyols [O] . Isao Kadota, Yueqing Hu, Garrick K. Packard, 2004

机译：天然产物合成特殊功能：多烯大环内酯类化合物的统一方法：candidin和nystatin多元醇的合成
7. A Carbohydrate-Based Approach for the Total Synthesis of 1, 3-Polyol/a-Pyrone Antifungal Natural Products [O] . -1

机译：一种基于碳水化合物的方法，用于总合成1,3-多元醇/ A-Pyrone抗真菌天然产物

A carbohydrate-based approach for the total synthesis of 1,3-polyol/alpha-pyrone antifungal natural products

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