Cooperative Catalysis Approach to Intramolecular Hydroacylation

摘要

Prior examples of hydroacylation to form sixandnseven-membered ring ketones require either embeddednchelating groups or other substrate design strategies toncircumvent competitive aldehyde decarbonylation. A cooperativencatalysis strategy enabled intramolecular hydroacylationnof disubstituted alkenes to form seven- and six-memberednrings without requiring substrate-embedded chelating groups.