Clinicopathological Significance of Macrophage Migration Inhibitory Factor and its Relation with P53 in Gastric Cancer

Majid Nabizadeh Marvast; Hamid Reza Sima; Kamran Ghaffarzadehgan; Ali Taghizadeh Kermani; Nona Norouzi

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Clinicopathological Significance of Macrophage Migration Inhibitory Factor and its Relation with P53 in Gastric Cancer

机译：巨噬细胞迁移抑制因子在胃癌中的临床病理意义及其与P53的关系

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Based on previous investigations, the progress of gastritis may lead to gastric carcinomas. In some epithelial tumors, macrophage migration inhibitory factor (MIF), which is an inflammatory cytokine may inactivate p53 and play a role in tumorigenesis process. We decided to evaluate clinicopathological significance of MIF expression and the relation between p53 and MIF expressions in gastric adenocarcinomas.

机译：根据以前的调查，胃炎的进展可能会导致胃癌。在某些上皮肿瘤中，炎性细胞因子巨噬细胞迁移抑制因子（MIF）可能使p53失活并在肿瘤发生过程中发挥作用。我们决定评估胃腺癌中MIF表达的临床病理意义以及p53和MIF表达之间的关系。

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来源
《Journal of Gastrointestinal Cancer》 |2011年第1期|p.5-10|共6页
作者
Majid Nabizadeh Marvast; Hamid Reza Sima; Kamran Ghaffarzadehgan; Ali Taghizadeh Kermani; Nona Norouzi;
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作者单位

Mashhad University Cancer Research Center, Mashhad University of Medical Sciences, Mashhad, Iran, 12th Emamat Street, Emamat Blvd, Number 18, PO Box: 91888-95611, Mashhad, Iran;

Department of Internal Medicine, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran;

Department of Pathology, Mashhad University Cancer Research Center, Omid Oncology Hospital, Mashhad University of Medical Sciences, Mashhad, 91866, Iran;

Department of Radiation Oncology, Mashhad University Cancer Research Center, Omid Oncology Hospital, Mashhad University of Medical Sciences, Mashhad, 91866, Iran;

Mashhad University Cancer Research Center, Mashhad University of Medical Sciences, Mashhad, Iran;

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正文语种 eng
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关键词
Macrophage migration inhibitory factor; Gastric adenocarcinomas; p53 tumor suppressor gene;

机译：巨噬细胞迁移抑制因子;胃腺癌;p53抑癌基因;

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1. Clinicopathological significance of macrophage migration inhibitory factor and its relation with p53 in gastric cancer. [J] . Nabizadeh Marvast M, Sima HR, Ghaffarzadehgan K, Journal of gastrointestinal cancer. . 2011,第1期

机译：巨噬细胞迁移抑制因子在胃癌中的临床病理学意义及其与p53的关系。
2. Gastric cancer susceptibility in gastric cancer relatives: Attributable risks of Macrophage migration inhibitory factor promoter polymorphism and Helicobacter pylori [J] . LiH., ZangJ., WangP., Cytokine . 2012,第2期

机译：胃癌亲属中的胃癌易感性：巨噬细胞迁移抑制因子启动子多态性和幽门螺杆菌的归因风险
3. Macrophage migration inhibitory factor as a potential prognostic factor in gastric cancer [J] . He Long-Jun, Xie Dan, Hu Pin-Jin, World journal of gastroenterology : . 2015,第34期

机译：巨噬细胞迁移抑制因子作为胃癌预后的潜在因素
4. Molecular function of macrophage migration inhibitory factor and a novel therapy for inflammatory bowel disease [C] . Jun Nishihira International Conference on Nutrition and Physical Activity in Aging, Obesity, and Cancer . 2012

机译：巨噬细胞迁移抑制因子的分子函数及炎性肠病的新疗法
5. Innate immunity in allergen-induced airway inflammation Role of macrophage migration inhibitory factor (MIF) and cholesterol 25-hydroxylase (CH25H) in alveolar macrophages. [D] . Park, Kiwon. 2011

机译：过敏原诱导的气道炎症中的先天免疫肺泡巨噬细胞中巨噬细胞迁移抑制因子（MIF）和胆固醇25-羟化酶（CH25H）的作用。
6. Increased epithelial and serum expression of macrophage migration inhibitory factor (MIF) in gastric cancer: potential role of MIF in gastric carcinogenesis [O] . X‐X He, J Yang, Y‐W Ding, 2006

机译：胃癌中巨噬细胞迁移抑制因子（MIF）的上皮和血清表达增加：MIF在胃癌发生中的潜在作用
7. Quantification of macrophage migration inhibitory factor mRNA expression in gastric cancer tissues and its clinical significance [O] . Y. Mohri, K. Tanaka, M. Ohi, 2011

机译：巨噬细胞迁移抑制因子mRNA表达在胃癌组织中的定量及其临床意义

Clinicopathological Significance of Macrophage Migration Inhibitory Factor and its Relation with P53 in Gastric Cancer

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