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Research Note: Binding of Aflatoxin B_1 Alters the Adhesion Properties of Lactobacillus rhamnosus Strain GG in a Caco-2 Model

机译:研究说明:黄曲霉毒素B_1的结合改变了Caco-2模型中鼠李糖乳杆菌GG菌株的粘附特性。

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Lactic acid bacteria have been previously reported to possess antimycotoxigenic activities both in vitro and in vivo. The objective of this study was to investigate the effect of aflatoxin B_1 on adhesion capability of Lactobacillus rhamnosus strain GG using a Caco-2 adhesion model. Removal of aflatoxin B_1 by L. Rhamnosus strain GG reduced the adhesion capability of This strain from 30/100 to 5/100. It is therefore concluded that aflatoxins may influence the adhesion properties of probiotics able To sequester them, and subsequently these bacteria may reduce the accumulation of aflatoxins in the intestine via increased Excretion of an aflatoxin-bacteria complex.
机译:先前已报道乳酸菌在体外和体内均具有抗霉菌毒素活性。这项研究的目的是使用Caco-2黏附模型研究黄曲霉毒素B_1对鼠李糖乳杆菌GG黏附能力的影响。鼠李糖乳杆菌GG对黄曲霉毒素B_1的去除使该菌株的粘附能力从30/100降低到5/100。因此得出结论,黄曲霉毒素可能会影响能够隔离它们的益生菌的粘附特性,随后这些细菌可能会通过增加黄曲霉毒素-细菌复合物的排泄量而减少黄曲霉毒素在肠道中的积累。

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