Sebaceous hyperplasia of the vulva: a clinicopathological case report with a review of the literature

摘要

Sebaceous hyperplasia consists of multiple asymptomatic small yellow papules with a central depression, occurring most commonly on the forehead and cheeks, but occasionally affecting the areola, chest or genital skin. The lesions are sometimes mistaken clinically for basal-cell carcinoma. Sebaceous hyperplasia belongs to the group of epidermal tumours with sebaceous differentiation. Farina el at suggested that hyperplasia in the sebaceous gland is analogous with trichofolliculoma. Although termed hyperplasia, they concluded that sebaceous hyperplasia is a benign neoplasm rather than hyperplasia as these lesions do not involute clinically. By contrast, the absence of significant enlargement of sebaceous lobules, and the sharp demarcation of the lesion distinguish it from hypertrophy. Thus, sebaceous hyperplasia is now considered as a hamartoma rather than a true neoplasm.