Impact of microsatellite testing and mismatch repair protein expression on the clinical interpretation of genetic testing in hereditary non-polyposis colorectal cancer

Robyn Ward; Cliff Meldrum; Rachael Williams; Elisa Mokany; Rodney Scott; Jenny Turner; Nicholas Hawkins; Bronwyn Burgess; Claire Groombridge; Allan Spigelman

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Impact of microsatellite testing and mismatch repair protein expression on the clinical interpretation of genetic testing in hereditary non-polyposis colorectal cancer

机译：微卫星检测和错配修复蛋白表达对遗传性非息肉性大肠癌基因检测临床解释的影响

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Abstract

机译：抽象

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来源
《Journal of Cancer Research and Clinical Oncology 》 |2002年第8期| 403-411| 共9页
作者
Robyn Ward; Cliff Meldrum; Rachael Williams; Elisa Mokany; Rodney Scott; Jenny Turner; Nicholas Hawkins; Bronwyn Burgess; Claire Groombridge; Allan Spigelman;
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作者单位

Department of Medical Oncology St Vincent's Hospital Victoria St. Darlinghurst NSW 2010 Australia;

Hunter Area Pathology Service John Hunter Hospital Newcastle NSW Australia;

St Vincent's Family Cancer Clinic St Vincent's Hospital Darlinghurst NSW Australia;

St Vincent's Family Cancer Clinic St Vincent's Hospital Darlinghurst NSW Australia;

Hunter Area Pathology Service John Hunter Hospital Newcastle NSW Australia;

Department of Anatomical Pathology St Vincent's Hospital Darlinghurst NSW Australia;

School of Medical Science University of NSW Sydney Australia;

Hunter Family Cancer Service Newcastle NSW Australia;

Hunter Family Cancer Service Newcastle NSW Australia;

Hunter Family Cancer Service Newcastle NSW Australia;

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正文语种 eng
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关键词
Colorectal carcinoma HNPCC Mismatch repair Microsatellite instability;

机译：大肠癌HNPCC错配修复微卫星不稳定性;

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专利

1. Impact of microsatellite testing and mismatch repair protein expression on the clinical interpretation of genetic testing in hereditary non-polyposis colorectal cancer. [J] . Ward R, Meldrum C, Williams R, Journal of Cancer Research and Clinical Oncology . 2002 ,第8期

机译：微卫星检测和错配修复蛋白表达对遗传性非息肉性大肠癌基因检测临床解释的影响。
2. Mismatch Repair mRNA and Protein Expression in Intestinal Adenocarcinoma in Sika Deer (Cervus nippon) Resembling Heritable Non-polyposis Colorectal Cancer in Man [J] . Jahns H., Browne J. A. Journal of Comparative Pathology . 2015 ,第2a3期

机译：类似于人类遗传性非息肉性结直肠癌的梅花鹿（小鹿）肠道腺癌中的错配修复mRNA和蛋白质表达
3. Molecular testing for microsatellite instability and DNA mismatch repair defects in hereditary and sporadic colorectal cancers--ready for prime time? [J] . Soreide K Tumour biology : . 2007 ,第5期

机译：对遗传性和散发性结直肠癌中的微卫星不稳定性和DNA错配修复缺陷进行分子测试-准备黄金时间了吗？
4. Patient identification and clinical management in hereditary non-polyposis colorectal cancer [C] . O. ALTAIE Falk Symposium . 2003

机译：遗传性非粘性结直肠癌患者的患者鉴定与临床管理
5. Psychometric testing of a scale designed to monitor the psychosocial and behavioral impact of genetic testing for hereditary nonpolyposis colorectal cancer (HNPCC): A pilot study. [D] . LeDrew, Holly. 2009

机译：旨在监测遗传性非息肉病性结直肠癌（HNPCC）的基因测试对心理和行为影响的量表的心理测试：一项试点研究。
6. DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer [O] . H Iino, L Simms, J Young, 2000

机译：遗传性非息肉病性结直肠癌中腺瘤的DNA微卫星不稳定性和错配修复蛋白损失
7. DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer [O] . Iino, H, Simms, L, Young, J, 2000

机译：遗传性非息肉病性结直肠癌中腺瘤的DNA微卫星不稳定性和错配修复蛋白损失

Impact of microsatellite testing and mismatch repair protein expression on the clinical interpretation of genetic testing in hereditary non-polyposis colorectal cancer

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