Reduction of connexin 43 in human cumulus cells yields good embryo competence during ICSI

Junichi Hasegawa; Atsushi Yanaihara; Shinji Iwasaki; Kaori Mitsukawa; Momoko Negishi; Takashi Okai

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Reduction of connexin 43 in human cumulus cells yields good embryo competence during ICSI

机译：人卵丘细胞中连接蛋白43的减少产生ICSI期间良好的胚胎能力

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摘要

The purpose of this study was to predict developmental competence of human oocytes during ICSI via analysis of connexin 43 (Cx43) in cumulus cells surrounding mature oocytes.

机译：这项研究的目的是通过分析成熟卵母细胞周围卵丘细胞中的连接蛋白43（Cx43）来预测ICSI期间人卵母细胞的发育能力。

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来源
《Journal of Assisted Reproduction and Genetics》 |2007年第10期|463-466|共4页
作者
Junichi Hasegawa; Atsushi Yanaihara; Shinji Iwasaki; Kaori Mitsukawa; Momoko Negishi; Takashi Okai;
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作者单位

Department of Obstetrics and Gynecology Showa University School of Medicine 1-5-8 Hatanodai Shinagawa-ku Tokyo 142-8666 Japan;

Department of Obstetrics and Gynecology Showa University School of Medicine 1-5-8 Hatanodai Shinagawa-ku Tokyo 142-8666 Japan;

Department of Obstetrics and Gynecology Showa University School of Medicine 1-5-8 Hatanodai Shinagawa-ku Tokyo 142-8666 Japan;

Department of Obstetrics and Gynecology Showa University School of Medicine 1-5-8 Hatanodai Shinagawa-ku Tokyo 142-8666 Japan;

Department of Obstetrics and Gynecology Showa University School of Medicine 1-5-8 Hatanodai Shinagawa-ku Tokyo 142-8666 Japan;

Department of Obstetrics and Gynecology Showa University School of Medicine 1-5-8 Hatanodai Shinagawa-ku Tokyo 142-8666 Japan;

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正文语种 eng
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关键词
Connexin 43; Gap junction; Cumulus cells; IVF; Embryo development;

机译：连接蛋白43;间隙连接;卵丘细胞;体外受精;胚胎发育;

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专利

1. Reduction of connexin 43 in human cumulus cells yields good embryo competence during ICSI. [J] . Hasegawa J, Yanaihara A, Iwasaki S, Journal of assisted reproduction and genetics . 2007,第10期

机译：人卵丘细胞中连接蛋白43的减少产生ICSI期间良好的胚胎能力。
2. Connexin 43 coupling in bovine cumulus cells, during the follicular growth phase, and its relationship to in vitro embryo outcomes [J] . Read Casey C., Willhelm Gabby, Dyce Paul W. Molecular reproduction and development . 2018,第7期

机译：Connexin 43在牛氏菌细胞中偶联，在卵泡生长阶段，及其与体外胚胎结果的关系
3. Biomarkers of human oocyte developmental competence expressed in cumulus cells before ICSI: a preliminary study. [J] . Assidi M, Montag M, Van der Ven K, Journal of assisted reproduction and genetics . 2011,第2期

机译：人类卵母细胞发育能力的生物标志物在ICSI之前在卵丘细胞中表达：一项初步研究。
4. Connective tissue growth factor (CTGF/CCN2) and Connexin-43 (0x43) expression are upregulated in human adipose-derived stromal cells (hASCs) over the course of osteogenic differentiation [C] . Panetta NJ, Gupta DM, Gupta A, International Society of Craniofacial Surgery International Congress . 2009

机译：在骨质发生分化的过程中，在人脂肪衍生的基质细胞（HASC）中，将结缔组织生长因子（CTGF / CCN2）和Connexin-43（0x43）表达上调
5. Mutations in Connexin43 and Connexin40 Associated with Human Atrial Fibrillation; Physiology and Mechanism. [D] . Thibodeau, Isabelle. 2010

机译：与人房颤相关的连接蛋白43和连接蛋白40的突变；生理机制。
6. Reduction of connexin 43 in human cumulus cells yields good embryo competence during ICSI [O] . Junichi Hasegawa, Atsushi Yanaihara, Shinji Iwasaki, 2007

机译：人卵丘细胞中连接蛋白43的减少产生ICSI期间良好的胚胎能力
7. Biomarkers of human oocyte developmental competence expressed in cumulus cells before ICSI: a preliminary study [O] . Assidi, Mourad, Montag, Markus, Van Der Ven, Katrin, 2010

机译：ICSI前卵丘细胞中表达的人类卵母细胞发育能力的生物标志物：初步研究

Reduction of connexin 43 in human cumulus cells yields good embryo competence during ICSI

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