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Intervention time series analysis of voluntary, counselling and testing on HIV infections in West African sub-region: the case of Ghana

机译:西非次区域艾滋病毒感染自愿,咨询和检测的干预时间序列分析:以加纳为例

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In this paper, intervention time series models were developed to examine the effectiveness of the voluntary counselling and testing (VCT) programme in the northern and southern sectors of Ghana. Pre-intervention data of HIV reported cases in the northern and southern sectors were first modelled as Box-Jenkins univariate time series. Second, the adopted models from the pre-intervention data were extended to include the intervention variable. The intervention variable was coded as zero for the pre-intervention period (1 January 1996-31 December 2002) and one for the post-intervention period (1 January 2003-31 December 2007). The models developed were applied to the entire data for the two sectors to estimate the effect of the VCT programme. Our findings indicate that the VCT programme was found to be associated with detection of 20 and 40 new HIV infections per 100,000 persons per month in the northern and southern sectors (p<.10), respectively. The VCT programme in Ghana, like most West African nations, has insignificant impact. Intervention time series models can be used to reliably examine the impact of the VCT programme. The impact of the VCT programme is minimal and we therefore recommend that the National AIDS Control Programme and other stakeholders re-double their efforts to maximise the impact of the programme.
机译:在本文中,开发了干预时间序列模型以检验加纳北部和南部地区自愿咨询和测试(VCT)计划的有效性。北部和南部地区艾滋病毒报告病例的干预前数据首先以Box-Jenkins单变量时间序列建模。其次,将干预前数据采用的模型扩展到包括干预变量。干预变量在干预前期间(1996年1月1日至2002年12月31日)编码为零,在干预后期间(2003年1月1日至2007年12月31日)编码为1。将开发的模型应用于两个部门的全部数据,以评估VCT计划的效果。我们的发现表明,在北部和南部地区,每月每100,000人中有20例和40例新的HIV感染被发现与VCT计划有关(p <.10)。像大多数西非国家一样,加纳的VCT计划影响不大。干预时间序列模型可用于可靠地检查VCT计划的影响。 VCT计划的影响微乎其微,因此我们建议国家艾滋病控制计划和其他利益相关者加倍努力以最大程度地发挥该计划的影响。

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