Sensitization of Campylobacter jejuni to fluoroquinolone and macrolide antibiotics by antisense inhibition of the CmeABC multidrug efflux transporter

Byeonghwa Jeon and Qijing Zhang*

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Sensitization of Campylobacter jejuni to fluoroquinolone and macrolide antibiotics by antisense inhibition of the CmeABC multidrug efflux transporter

机译：通过反义抑制CmeABC多药外排转运蛋白使空肠弯曲杆菌对氟喹诺酮和大环内酯类抗生素敏感

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Objectives The aim of this study was to investigate the feasibility and efficacy of antisense-mediated gene silencing by peptide nucleic acid (PNA) for specific inactivation of the CmeABC multidrug efflux transporter in Campylobacter jejuni.

机译：目的这项研究的目的是研究空肠弯曲菌中CmeABC多药外排转运蛋白的特异性灭活，由肽核酸（PNA）进行的反义介导的基因沉默的可行性和有效性。

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《Journal of Antimicrobial Chemotherapy》 |2009年第5期|p.946-948|共3页
作者
Byeonghwa Jeon and Qijing Zhang*;
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Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA;

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1. Sensitization of Campylobacter jejuni to fluoroquinolone and macrolide antibiotics by antisense inhibition of the CmeABC multidrug efflux transporter. [J] . Jeon B, Zhang Q The Journal of Antimicrobial Chemotherapy . 2009,第5期

机译：通过反义抑制CmeABC多药外排转运蛋白，使空肠弯曲杆菌对氟喹诺酮和大环内酯类抗生素敏感。
2. Target optimization for peptide nucleic acid (PNA)-mediated antisense inhibition of the CmeABC multidrug efflux pump in Campylobacter jejuni [J] . OhE., ZhangQ., JeonB. The Journal of Antimicrobial Chemotherapy . 2014,第2期

机译：空肠弯曲菌中CmeABC多药外排泵的肽核酸（PNA）介导的反义抑制的靶点优化
3. Contribution of the multidrug efflux transporter CmeABC to antibiotic resistance in different Campylobacter species. [J] . Guo B, Lin J, Reynolds D Foodborne pathogens and disease . 2010,第1期

机译：多药外排转运蛋白CmeABC在不同弯曲杆菌属中对抗生素抗性的贡献。
4. The Biocide and Antibiotic Resistance in Campylobacter jejuni and Campylobacter coli [C] . Ana Mavri, Urska Ribic, Sonja Smole Mozina Central European Congress on Food . 2016

机译：Jejuni和Campylobacter Coli的杀菌剂和抗生素抗性
5. Inhibition of the CmeABC Efflux Pump by Antisense Peptide Nucleic Acids Reduces the Emergence of Spontaneous Fluoroquinolone Resistant Mutants in Campylobacter jejuni [D] . ?Singh, Kritika 2020

机译：通过反义肽核酸抑制CMEABC渗透泵减少了云津楚楚氏杆菌的自发氟喹啉抗突变体的出现
6. Sensitization of Campylobacter jejuni to fluoroquinolone and macrolide antibiotics by antisense inhibition of the CmeABC multidrug efflux transporter [O] . Byeonghwa Jeon, Qijing Zhang -1

机译：通过反义抑制CmeABC多药外排转运蛋白使空肠弯曲杆菌对氟喹诺酮和大环内酯类抗生素敏感
7. Sensitization of Campylobacter jejuni to fluoroquinolone and macrolide antibiotics by antisense inhibition of the CmeABC multidrug efflux transporter [O] . Jeon, Byeonghwa, Zhang, Qijing 2009

机译：通过反义抑制CmeABC多药外排转运蛋白使空肠弯曲杆菌对氟喹诺酮和大环内酯类抗生素敏感

Sensitization of Campylobacter jejuni to fluoroquinolone and macrolide antibiotics by antisense inhibition of the CmeABC multidrug efflux transporter

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