Stability of phosphatidylethanol species in spiked and authentic whole blood and matching dried blood spots

Andrea Faller; Barbara Richter; Matthias Kluge; Patrick Koenig; H. K. Seitz; Gisela Skopp

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Stability of phosphatidylethanol species in spiked and authentic whole blood and matching dried blood spots

机译：加标和真实的全血以及相匹配的干血斑中磷脂酰乙醇物质的稳定性

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Background Phosphatidylethanol (PEth) is currently under investigation as a highly sensitive and specific marker of alcohol misuse. As its stability in blood samples has not systematically been investigated, a study was performed to determine the stability of major PEth species in spiked and authentic whole blood and also in matching dried blood spots (DBS) at different conditions.

机译：背景技术磷脂酰乙醇（PEth）目前正作为酒精滥用的高度敏感和特异标志物进行研究。由于尚未系统研究其在血液样本中的稳定性，因此进行了一项研究以确定主要PEth物种在加标和真实的全血中以及在不同条件下在匹配的干血斑（DBS）中的稳定性。

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来源
《International Journal of Legal Medicine》 |2013年第3期|603-610|共8页
作者
Andrea Faller; Barbara Richter; Matthias Kluge; Patrick Koenig; H. K. Seitz; Gisela Skopp;
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作者单位

Institute of Legal and Traffic Medicine University Hospital Heidelberg">(1);

Psychiatric Center Nordbaden">(2);

Psychiatric Center Nordbaden">(2);

Salem Medical Center">(3);

Salem Medical Center">(3);

Institute of Legal and Traffic Medicine University Hospital Heidelberg">(1);

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原文格式 PDF
正文语种 eng
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关键词
Stability; Dried blood spots; Whole blood; Phosphatidylethanol; LC-MS/MS;

机译：稳定性;干血斑;全血;磷脂酰乙醇;液质联用;

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1. Stability of phosphatidylethanol species in spiked and authentic whole blood and matching dried blood spots [J] . FallerA., RichterB., KlugeM., International journal of legal medicine . 2013,第3期

机译：尖刺和正宗全血中磷脂酰乙醇种类的稳定性，匹配干血斑
2. Degradation of zopiclone during storage of spiked and authentic whole blood and matching dried blood spots [J] . JantosR., VermeerenA., SabljicD., International journal of legal medicine . 2013,第1期

机译：佐匹克隆的存储过程中佐加酮和纯正全血以及匹配的干血斑的降解
3. Degradation of zopiclone during storage of spiked and authentic whole blood and matching dried blood spots [J] . Ricarda Jantos, Annemiek Vermeeren, Danica Sabljic, International Journal of Legal Medicine . 2013,第1期

机译：佐匹克隆的储存过程中佐加酮和纯正全血以及匹配的干血斑的降解
4. Improved Stability of Unstable Compounds in Blood using Dry Blood Spotting (DBS) Technique Followed by LC-MS/MS Analysis. [C] . Udeni Yapa, Ileana Ionita, Rick Steenwyk American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2010

机译：使用干血液斑点（DBS）技术，改善了血液中不稳定化合物的稳定性，然后是LC-MS / MS分析。
5. Development of Newborn Screening Methods for Mucopolysaccharidosis III Type A and Type B in Dried Blood Spot Using Tandem Mass Spectrometry [D] . Yi, Fan. 2018

机译：使用串联质谱法，在干血液点粘性型A和型B型和型B的新生筛查方法的开发
6. Stability of Phosphatidylethanol in Dry Blood Spot Cards [O] . Ludmila N. Bakhireva, Shikhar Shrestha, Hilda L. Gutierrez, -1

机译：干血点卡中磷脂酰乙醇的稳定性
7. Stability of Phosphatidylethanol in Dry Blood Spot Cards [O] . Ludmila N. Bakhireva, Shikhar Shrestha, Hilda L. Gutierrez, 2015

机译：干血斑牌中磷脂基乙醇的稳定性

Stability of phosphatidylethanol species in spiked and authentic whole blood and matching dried blood spots

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