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Efficiency and safety evaluation of photodegradation of Aflatoxin B_1 on peanut surface

机译:黄曲霉毒素B_1在花生表面光降解的效率和安全性评价。

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摘要

A photodegradation study of Aflatoxin B_1 (AFB_1) on peanut surface was performed under UV irradiation at different UV irradiation intensities. With an initial quantity of 10 ng of AFB_1, it can be degraded thoroughly within 80 min under the intensity of 800 μw cm~(-2). The photodegradation pathway of AFB_1 on the peanut surface was proposed. Mutagenesis and cytotoxicity were assessed after exposure to different concentrations of AFB_1 and the mixtures of photodegradation products on the peanut surface. The results of the Ames and in vitro cytotoxicity assay, providing clues to the assessment of safety issues of UV method applied in AFB_1 decontamination, indicate that photodegradation products on the peanut surface has no toxicity, which can be explained by the differences in the chemical nature of the test compounds before and after UV irradiation.
机译:在不同的紫外线照射强度下,在紫外线下进行了黄曲霉毒素B_1(AFB_1)在花生表面的光降解研究。初始量为10 ng的AFB_1,可在80分钟内在800μwcm〜(-2)的强度下彻底降解。提出了花生表面AFB_1的光降解途径。暴露于不同浓度的AFB_1和花生表面上的光降解产物混合物后,评估其诱变和细胞毒性。 Ames和体外细胞毒性试验的结果为评估AFB_1去污中使用的紫外线方法的安全性问题提供了线索,表明花生表面的光降解产物没有毒性,这可以用化学性质的差异来解释。在紫外线照射之前和之后的测试化合物。

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  • 作者单位

    State Key Laboratory of Food Science and Safety, Synergetic Innovation Center of Food Safety and Nutrition, School of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, Jiangsu, China;

    State Key Laboratory of Food Science and Safety, Synergetic Innovation Center of Food Safety and Nutrition, School of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, Jiangsu, China;

    State Key Laboratory of Food Science and Safety, Synergetic Innovation Center of Food Safety and Nutrition, School of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, Jiangsu, China;

    State Key Laboratory of Food Science and Safety, Synergetic Innovation Center of Food Safety and Nutrition, School of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, Jiangsu, China;

    State Key Laboratory of Food Science and Safety, Synergetic Innovation Center of Food Safety and Nutrition, School of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, Jiangsu, China;

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  • 正文语种 eng
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  • 关键词

    Aflatoxin B_1; Ames test; cell toxicity; photodegradation products; UPLC-Q-TOF/MS;

    机译:黄曲霉毒素B_1;艾姆斯测试;细胞毒性;光降解产物;UPLC-Q-TOF / MS;

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