Gene expression profiles in stages II and III colon cancers: application of a 128-gene signature

Morten Thorsteinsson; Lene T. Kirkeby; Raino Hansen; Leif R. Lund; Lars T. Sørensen; Thomas A. Gerds; Per Jess; Jørgen Olsen

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Gene expression profiles in stages II and III colon cancers: application of a 128-gene signature

机译：II和III期结肠癌的基因表达谱：128基因签名的应用

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摘要

A 128-gene signature has been proposed to predict outcome in patients with stages II and III colorectal cancers. In the present study, we aimed to reproduce and validate the 128-gene signature in external and independent material.

机译：已经提出了128基因签名来预测II期和III期结直肠癌患者的预后。在本研究中，我们旨在重现和验证外部和独立材料中的128基因签名。

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来源
《International Journal of Colorectal Disease》 |2012年第12期|p.1579-1586|共8页
作者
Morten Thorsteinsson; Lene T. Kirkeby; Raino Hansen; Leif R. Lund; Lars T. Sørensen; Thomas A. Gerds; Per Jess; Jørgen Olsen;
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作者单位

Department of Surgery, Roskilde Hospital, Faculty of Health Sciences, University of Copenhagen, Koegevej 7-13, 4000, Roskilde, Denmark;

Department of Surgery, Roskilde Hospital, Faculty of Health Sciences, University of Copenhagen, Koegevej 7-13, 4000, Roskilde, Denmark;

Department of Cellular and Molecular Medicine, Faculty of Health Sciences, University of Copenhagen, Roskilde, Denmark;

Department of Cellular and Molecular Medicine, Faculty of Health Sciences, University of Copenhagen, Roskilde, Denmark;

Department of Surgery K, Bispebjerg Hospital, Faculty of Health Sciences, University of Copenhagen, Roskilde, Denmark;

Department of Biostatistics, Faculty of Health Sciences, University of Copenhagen, Roskilde, Denmark;

Department of Surgery, Roskilde Hospital, Faculty of Health Sciences, University of Copenhagen, Koegevej 7-13, 4000, Roskilde, Denmark;

Department of Cellular and Molecul;

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原文格式 PDF
正文语种 eng
中图分类
关键词
Gene expression profiles; Molecular markers; Colon cancer; Relapse and prognosis;

机译：基因表达谱;分子标记;结肠癌;复发和预后;

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1. Gene expression profiles in stages II and III colon cancers: application of a 128-gene signature. [J] . Morten Thorsteinsson, Lene T Kirkeby, Raino Hansen, International journal of colorectal disease. . 2012,第12期

机译：II期和III期结肠癌的基因表达谱：128个基因签名的应用。
2. Gene-expression signature of tumor recurrence in patients with stage II and III colon cancer treated with 5′fluoruracil-based adjuvant chemotherapy [J] . GiráldezM.D., LozanoJ.J., CuatrecasasM., International Journal of Cancer =: Journal International du Cancer . 2013,第5期

机译：用5'Fluorurcil的佐剂化疗治疗II期和III结肠癌患者肿瘤复发的基因表达特征
3. Stage III & IV colon and rectal cancers share a similar genetic profile: A review of the Oregon Colorectal Cancer Registry [J] . GawlickU., LuK.C., DouthitM.A., The American Journal of Surgery . 2013,第5期

机译：III和IV期结肠癌和直肠癌具有相似的遗传特征：俄勒冈结直肠癌注册中心的评论
4. Colon Cancer Prediction from Gene Expression Profiles Using Kernel Based Support Vector Machine [C] . Md. Abu Horaira, Md. Shakil Ahmed, Md. Hadiul Kabir, 2018 International Conference on Computer, Communication, Chemical, Material and Electronic Engineering . 2018

机译：基于内核的支持向量机从基因表达谱预测结肠癌
5. The Association of Hospital and Patient Characteristics with Treatment Initiation among Veterans with Stage I, II, or III Lung, Colon or Rectal Cancer [D] . Clary, Alecia S. 2019

机译：具有阶段I，II或III肺，结肠或直肠癌的退伍军人治疗发起的医院和患者特征
6. Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients [O] . Evert van den Broek, Oscar Krijgsman, Daoud Sie, 2016

机译：II期和III期结肠癌的基因组分析显示APC突变与III期结肠癌患者的存活率相关
7. Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients [O] . Evert van den Broek, Oscar Krijgsman, Daoud Sie, 2016

机译：II期和III结肠癌的基因组分析揭示了与III期结肠癌患者的存活相关的APC突变

Gene expression profiles in stages II and III colon cancers: application of a 128-gene signature

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