Salvage chemotherapy with paclitaxel and gemcitabine plus nedaplatin (TGN) as part of multidisciplinary therapy in patients with heavily pretreated cisplatin-refractory germ cell tumors

Takumi Shiraishi; Terukazu Nakamura; Kazuya Mikami; Natsuki Takaha; Akihiro Kawauchi; Tsuneharu Miki

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Salvage chemotherapy with paclitaxel and gemcitabine plus nedaplatin (TGN) as part of multidisciplinary therapy in patients with heavily pretreated cisplatin-refractory germ cell tumors

机译：紫杉醇联合吉西他滨加奈达铂（TGN）进行挽救性化疗，作为多学科疗法的一部分，用于高度预处理的顺铂难治性生殖细胞肿瘤患者

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We investigated the efficacy and toxicity of a regimen consisting of paclitaxel and gemcitabine plus nedaplatin, a derivative of cisplatin (TGN) in patients with heavily pretreated cisplatin-refractory germ cell tumors (GCTs).

机译：我们研究了由紫杉醇和吉西他滨加奈达铂（一种顺铂衍生物（TGN））组成的方案在经过大量预处理的顺铂难治性生殖细胞肿瘤（GCT）患者中的疗效和毒性。

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来源
《International Journal of Clinical Oncology》 |2009年第5期|436-441|共6页
作者
Takumi Shiraishi; Terukazu Nakamura; Kazuya Mikami; Natsuki Takaha; Akihiro Kawauchi; Tsuneharu Miki;
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作者单位

Department of Urology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kawaramachi-Hirokoji Kamigyo-ku Kyoto 602-8566 Japan;

Department of Urology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kawaramachi-Hirokoji Kamigyo-ku Kyoto 602-8566 Japan;

Department of Urology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kawaramachi-Hirokoji Kamigyo-ku Kyoto 602-8566 Japan;

Department of Urology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kawaramachi-Hirokoji Kamigyo-ku Kyoto 602-8566 Japan;

Department of Urology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kawaramachi-Hirokoji Kamigyo-ku Kyoto 602-8566 Japan;

Department of Urology Graduate School of Medical Science Kyoto Prefectural University of Medicine Kawaramachi-Hirokoji Kamigyo-ku Kyoto 602-8566 Japan;

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正文语种 eng
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关键词
Germ cell tumor; Salvage chemotherapy; Paclitaxel; Gemcitabine; Nedaplatin;

机译：生殖细胞肿瘤;挽救性化疗;紫杉醇;吉西他滨;奈达铂;

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专利

1. Salvage chemotherapy with paclitaxel and gemcitabine plus nedaplatin (TGN) as part of multidisciplinary therapy in patients with heavily pretreated cisplatin-refractory germ cell tumors. [J] . Shiraishi T, Nakamura T, Mikami International journal of clinical oncology . 2009,第5期

机译：紫杉醇联合吉西他滨加奈达铂（TGN）进行挽救性化疗，作为多学科疗法的一部分，用于患有严重预处理的顺铂难治性生殖细胞肿瘤的患者。
2. Combination chemotherapy with gemcitabine, oxaliplatin, and paclitaxel in patients with cisplatin-refractory or multiply relapsed germ-cell tumors: a study of the German Testicular Cancer Study Group. [J] . Bokemeyer C, Oechsle K, Honecker F, Annals of oncology: official journal of the European Society for Medical Oncology . 2008,第3期

机译：吉西他滨，奥沙利铂和紫杉醇联合化疗治疗顺铂难治性或多重复发性生殖细胞肿瘤的患者：德国睾丸癌研究小组的一项研究。
3. Combination chemotherapy with gemcitabine, oxaliplatin, and paclitaxel in patients with cisplatin-refractory or multiply relapsed germ-cell tumors: a study of the German Testicular Cancer Study Group [J] . C. Bokemeyer1? K. Oechsle1? F. Honecker1 F. Mayer3 J. T. Hartmann3 C. F. Waller4 I. B?hlke1 and C. Kollmannsberger23 Annals of Oncology . 2008,第3期

机译：吉西他滨，奥沙利铂和紫杉醇联合化疗治疗顺铂难治性或多重复发性生殖细胞肿瘤的患者：德国睾丸癌研究小组的一项研究
4. Is High-Dose Chemotherapy Plus Stem-Cell Transplant the Standard Treatment for Patients Failing First-Line Chemotherapy for Metastatic Germ Cell Tumor? [C] . Christian Kollmannsberger, Lawrence Einhorn, Craig Nichols Genitourinary Cancers Symposium. . 2014

机译：高剂量化疗加干细胞移植对转移细胞肿瘤的一线化疗失败的患者的标准治疗吗？
5. Predictive factors of the treatment outcome in patients with advanced biliary tract cancer receiving gemcitabine plus cisplatin as first-line chemotherapy [D] . 鈴木, 裕子 2019

机译：吉西他滨联合顺铂一线化疗对晚期胆道癌患者治疗效果的预测因素
6. Thrombotic thrombocytopenic purpura following salvage chemotherapy with paclitaxel ifosfamide and cisplatin in a patient with a refractory germ cell tumor: A case report and review of the literature [O] . ARIFE ULAS, KAMILE SILAY, SEMA AKINCI, -1

机译：紫杉醇异环磷酰胺和顺铂对难治性生殖细胞肿瘤患者进行挽救性化疗后的血栓性血小板减少性紫癜：一例并文献复习
7. Prognostic impact of progression to induction chemotherapy and prior paclitaxel therapy in patients with germ cell tumors receiving salvage high-dose chemotherapy in the last 10 years: a study of the European Society for Blood and Marrow Transplantation Solid Tumors Working Party [O] . Necchi, Andrea, Miceli, R., Laszlo, D., 2016

机译：近十年来接受诱导化疗和先前紫杉醇治疗对生殖细胞肿瘤患者进行挽救性大剂量化疗的预后影响：欧洲血液和骨髓移植实体瘤工作组的研究

Salvage chemotherapy with paclitaxel and gemcitabine plus nedaplatin (TGN) as part of multidisciplinary therapy in patients with heavily pretreated cisplatin-refractory germ cell tumors

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