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Oxaliplatin-induced allergic reaction in patients with colorectal cancer in Japan

机译：日本奥沙利铂对大肠癌患者的过敏反应

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摘要

Oxaliplatin is a platinum compound that is clinically effective for colorectal cancer (CRC), in combination with 5-fluorouracil (5-FU) and leucovorin (LV), and it is widely used for metastatic disease and for the adjuvant treatment of stage III CRC. With the increasing use of oxaliplatin in Japan, serious adverse events have been experienced other than hematologic and neurologic toxicities.
机译：奥沙利铂是一种临床上对结直肠癌（CRC）有效的铂类化合物，与5-氟尿嘧啶（5-FU）和亚叶酸（LV）结合使用，广泛用于转移性疾病和III期CRC的辅助治疗。在日本，随着奥沙利铂使用的增加，除血液和神经毒性外，还出现了严重的不良事件。

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  • 来源
    《International Journal of Clinical Oncology》 |2009年第5期|397-401|共5页
  • 作者

    Yoshihiro Shibata; Hiroshi Ariyama; Eishi Baba; Yasushi Takii; Taito Esaki; Kenji Mitsugi; Tanji Tsuchiya; Hitoshi Kusaba; Koichi Akashi; Shuji Nakano;

  • 作者单位

    Department of Medicine and Biosystemic Science Kyushu University Graduate School of Medical Sciences 3-1-1 Maidashi Higashi-ku Fukuoka 812-8582 Japan;

    Department of Gastrointestinal and Medical Oncology National Hospital Organization Kyushu Cancer Center Fukuoka Japan;

    Department of Medicine and Biosystemic Science Kyushu University Graduate School of Medical Sciences 3-1-1 Maidashi Higashi-ku Fukuoka 812-8582 Japan;

    Department of Medicine and Biosystemic Science Kyushu University Graduate School of Medical Sciences 3-1-1 Maidashi Higashi-ku Fukuoka 812-8582 Japan;

    Department of Gastrointestinal and Medical Oncology National Hospital Organization Kyushu Cancer Center Fukuoka Japan;

    Department of Medical Oncology Hamanomachi Hospital Fukuoka Japan;

    Department of Internal Medicine Sawara Hospital Fukuoka Japan;

    Department of Medicine and Biosystemic Science Kyushu University Graduate School of Medical Sciences 3-1-1 Maidashi Higashi-ku Fukuoka 812-8582 Japan;

    Department of Medicine and Biosystemic Science Kyushu University Graduate School of Medical Sciences 3-1-1 Maidashi Higashi-ku Fukuoka 812-8582 Japan;

    Department of Medicine and Biosystemic Science Kyushu University Graduate School of Medical Sciences 3-1-1 Maidashi Higashi-ku Fukuoka 812-8582 Japan;

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  • 原文格式 PDF
  • 正文语种 eng
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  • 关键词

    Colorectal cancer; Oxaliplatin; Allergic reaction;

    机译：大肠癌;奥沙利铂;过敏反应;

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