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Prognostic relevance of KRAS and BRAF mutations in Japanese patients with colorectal cancer

机译:日本大肠癌患者KRAS和BRAF突变的预后相关性

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摘要

Background Mutations of the KRAS or BRAF genes are now recognized as prognostic markers for colorectal cancer (CRC). They are also important predictive markers for resistance to the monoclonal antibodies that target the epidermal growth factor receptor.
机译:KRAS或BRAF基因的背景突变现已被认为是结直肠癌(CRC)的预后标记。它们也是针对靶向表皮生长因子受体的单克隆抗体的抗性的重要预测标记。

著录项

  • 来源
    《International Journal of Clinical Oncology》 |2013年第6期|1042-1048|共7页
  • 作者单位

    Department of Surgery and Science Graduate School of Medical Sciences Kyushu University">(1);

    Department of Molecular Oncology Graduate School of Medical Sciences Kyushu University">(2);

    Department of Surgery and Science Graduate School of Medical Sciences Kyushu University">(1);

    Department of Surgery and Science Graduate School of Medical Sciences Kyushu University">(1);

    Department of Molecular Oncology Graduate School of Medical Sciences Kyushu University">(2);

    Department of Surgery and Science Graduate School of Medical Sciences Kyushu University">(1);

    Department of Surgery and Science Graduate School of Medical Sciences Kyushu University">(1);

    Department of Surgery and Science Graduate School of Medical Sciences Kyushu University">(1);

    Department of Surgery and Science Graduate School of Medical Sciences Kyushu University">(1);

    Department of Surgery and Science Graduate School of Medical Sciences Kyushu University">(1);

    Department of Molecular Oncology Graduate School of Medical Sciences Kyushu University">(2);

    Department of Surgery and Science Graduate School of Medical Sciences Kyushu University">(1);

    Department of Surgery and Science Graduate School of Medical Sciences Kyushu University">(1);

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    KRAS and BRAF mutations; Colorectal cancer; Prognostic factor;

    机译:KRAS和BRAF突变;大肠癌;预后因素;

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