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Functionalized Silica Coated Magnetic Nanoparticles With Biological Species for Magnetic Separation

机译:具有生物分离功能的功能化的二氧化硅涂层磁性纳米粒子。

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摘要

Magnetic nanoparticle captured in a thin functional coating as magnetic separable nano-vehicle for carrying chemical species is a hot and challenging area. Here, we report a synthesis of silica encapsulated magnetic nanosize particles (4–11 nm) as a magnetic separable carrier based on a simple microemulsion technique. The silica coating surface is shown to isolate and protect the magnetic core from reactive environment where a range of conditions for magnetic separation can be made possible. Thus, it is demonstrated that the relatively smaller size coated magnetic nanoparticle can carry bulky protein, the bovine serum albumin (BSA) on the silica overlayer surface, which is confirmed by the FTIR study.
机译:在薄的功能性涂层中捕获的磁性纳米颗粒作为用于运载化学物质的磁性可分离纳米载体,是一个热门且充满挑战的领域。在这里,我们报告基于简单的微乳化技术的二氧化硅包裹的磁性纳米尺寸颗粒(4-11 nm)的合成,作为磁性可分离的载体。示出了二氧化硅涂层表面将磁芯隔离并保护磁芯不受反应环境的影响,在反应环境中可以实现一系列的磁分离条件。因此,证明了相对较小尺寸的涂覆的磁性纳米颗粒可以在二氧化硅覆盖层表面上携带大体积的蛋白质,即牛血清白蛋白(BSA),这已被FTIR研究证实。

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