Einfluß unterschiedlicher Lebensabschnitte auf die belastungsabhängige Reaktion ossärer Risikofaktoren einer Osteoporose

摘要

We investigated the effect of a 9-month physical training programme on BMD, total body calcium and mean lumbar vertebral bone width in women in different periods of their life. 46 women (55 ± 6 y) without medication affecting bone metabolism took part at our intensive and high frequency (> 2-4 times/week) training programme, 18 Persons (56 ± 8 y) served as non-training control. For the analysis all trained women were divided into three subgroups of women in different periods of their life (pre-menopausal, n=14; early postmenopau-sal: < 8 years postmenopausal, n=15; late postmenopausal: > 8 years postmenopausal, n=17). BMD-, total body calcium- and mean lumbar vertebral bone width (DXA) increases (%) were averaged for each group. For the premenopausal subgroup we could demonstrate a significant increase (+1.9%) at the lumbar spine and smaller (n.s.) increases at the femoral neck region, the total-body-calcium and the mean lumbar vertebral bone width. A slight decrease occured for wards triaangle BMD. The early postmenopausal women showed a significant increase for the lumbar spine BMD (+2.5%). Increases at the femoral neck region , total body calcium and for the mean lumbar vertebral bone width were smaller and not significant. For the subgroup in the late postmenopausal period we could demonstrate significant increases in BMD of the lumbar spine (+1.8%). Slight increases (n.s.) we could show for the neck region, at ward's triaangle, for the trochante-ric region and the mean lumbar vertebral bone width. No alteration could be detected for the total body calcium. Comparing the results of the three subgroups in different life-periods no significant differences could be demonstrated for any parameter. Comparing to the results of the non-training control group, there were remarkable and statistically significant (BMD-LS) differences. We conclude that an intensive and high-frequency training programme under regard of recent development of physical sciences can improve bone density, total body calcium and mean lumbar vertebral bone width in adolescent women (with some limitations) independent of their period of life.%Wir untersuchten die Auswirkungen eines 9monatigen körperlichen Trainings auf ossäre Risikofaktoren einer Osteoporose bei Frauen in unterschiedlichen Lebensabschnitten (prämenopausal vs. früh- und spät-postmenopausal). 46 Frauen (55 ± 6 J.) ohne Medikation mit Wirkung auf den Knochenstoffwechsel nahmen an der intensiven und häufigen (> 2 - 4mal/Woche) Trainingsmaßnahme teil, 18 Personen (56 ± 8 J.) dienten als Kontrollgruppe. Nach Trichotomisierung des Gesamtkollektivs zeigte die prämenopausale Gruppe (n=14; 44 ± 5 J.) an der LWS-Regi-on eine signifikante Verbesserung (+1.9%) der Knochendichte (DXA). Für die Schenkelhalsregion, das Gesamtkalzium und die Breite der Lendenwirbelkörper 2-4 konnten keine wesentlichen Veränderungen erfaßt werden. Die früh-postme-nopausale Frauengruppe (n=15; 54 ± 5 J.) zeigte eine sehr signifikante Verbesserung (+2.5%) an der LWS, sowie deutliche (n.s.) Verbesserungen des Gesamt-Kalziums (+1.4%), der Knochendichte am Ward'-schen Dreieck (+1.3%) und Trochanter (+1.1%). Keine wesentlichen Veränderungen zeigten sich für die Knochendichte am Schenkelhals und für die Breite der LWK 2-4.