Fukuronori (Gloiopeltis furcata) Extract: 90-Day Dietary Toxicity Study in F344 Rats

摘要

Fukuronori extract (FE), which is mainly composed of polysaccharides, and is an extract of the seaweed Gloiopeltis furcata, is permitted for use as a food thickening agent by the Ministry of Health and Welfare, Japan. In order to study the subchronic toxicity of FE, F344 rats of both Genders were administered FE at concentrations of 0/100 (basal diet, control group), 0.5/100, 1.5/100 and 5.0/100 in basal powder diet for 90 days, and observation of general condition, recording of body weight and food consumption, examination of hematology and blood chemistry, measurement of organ weight, and pathological examination were performed.