Cyclohexane-1,2-dicarboxylic acid diisononyl ester and metabolite effects on rat epididymal stromal vascular fraction differentiation of adipose tissue (2015) Environmental Research 140:145-156 Reply to the letter by Otter R

摘要

Dear Dr. Domingo, Thank you for the opportunity to respond to the comments made by Dr. Otter. First, we would like to note that our manuscript presented data obtained in vitro, showing effects of MINCH and not DINCH, on preadipocyte differentiation. In the discussion section, the potential environmental risk associated with DINCH exposure was presented as speculation. Moreover, no publicly available peer-reviewed information was missed since the regulatory information listed in Dr. Otter' letter was cited either directly (European Food Safety Authority, 2006) or indirectly through referencing a critical review of the DINCH literature (Bhat et al., 2014). A point-per-point reply follows.