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Pregnancy exposure to atmospheric pollution and meteorological conditions and placental DNA methylation

机译:怀孕暴露于大气污染和气象条件以及胎盘DNA甲基化

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摘要

Background: Air pollution exposure represents a major health threat to the developing foetus. DNA methylation is one of the most well-known molecular determinants of the epigenetic status of cells. Blood DNA methylation has been proven sensitive to air pollutants, but the molecular impact of air pollution on new-borns has so far received little attention.
机译:背景:空气污染暴露是对发育中的胎儿的主要健康威胁。 DNA甲基化是细胞表观遗传状态最著名的分子决定因素之一。血液中的DNA甲基化已被证明对空气污染物敏感,但迄今为止,空气污染对新生儿的分子影响几乎未引起关注。

著录项

  • 来源
    《Environment international》 |2018年第9期|334-347|共14页
  • 作者单位

    Univ Grenoble Alpes, CNRS, INSERM, IAB, F-38000 Grenoble, France;

    Univ Grenoble Alpes, CNRS, INSERM, IAB, F-38000 Grenoble, France;

    Univ Grenoble Alpes, CNRS, INSERM, IAB, F-38000 Grenoble, France;

    Univ Grenoble Alpes, CNRS, INSERM, IAB, F-38000 Grenoble, France;

    CEA Inst Biol Francois Jacob, Lab Epigenet & Environm, Ctr Natl Rech Genom Humaine, Evry, France;

    Air Lorraine, Nancy, France;

    ATMO Poitou Charentes, La Rochelle, France;

    Univ Grenoble Alpes, CNRS, INSERM, IAB, F-38000 Grenoble, France;

    Paris Descartes Univ, Genom Epigenet & Physiopathol Reprod, Inst Cochin, U1016,Inserm,UMR 8104,CNRS, Paris, France;

    Paris Descartes Univ, Early Origins Child Hlth & Dev Team, Res Ctr Epidemiol & Biostat, Inserm U1153,Sorbonne Paris Cite,CRESS, Villejuif, France;

    Paris Descartes Univ, Early Origins Child Hlth & Dev Team, Res Ctr Epidemiol & Biostat, Inserm U1153,Sorbonne Paris Cite,CRESS, Villejuif, France;

    Paris Descartes Univ, Early Origins Child Hlth & Dev Team, Res Ctr Epidemiol & Biostat, Inserm U1153,Sorbonne Paris Cite,CRESS, Villejuif, France;

    Harvard TH Chan Sch Publ Hlth, Dept Environm Hlth, Boston, MA USA;

    Univ Grenoble Alpes, CNRS, INSERM, IAB, F-38000 Grenoble, France;

    Univ Grenoble Alpes, CNRS, INSERM, IAB, F-38000 Grenoble, France;

    Univ Grenoble Alpes, CNRS, INSERM, IAB, F-38000 Grenoble, France;

    Univ Grenoble Alpes, CNRS, INSERM, IAB, F-38000 Grenoble, France;

    Univ Grenoble Alpes, CNRS, INSERM, IAB, F-38000 Grenoble, France;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Mother-child cohort; Placenta; Air pollution; Epigenetics; Temperature; Humidity;

    机译:母婴队列;胎盘;空气污染;表观遗传学;温度;湿度;

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