Exon sequencing and association analysis of polymorphisms in TCF7L2 with type 2 diabetes in a Chinese population

摘要

Aims/hypothesis Recently, variants in the transcription factor 7-like 2 (TCF7L2) gene have been found to be consistently associated with type 2 diabetes in different populations. In this study, we hypothesized that TCF7L2 also contributed to genetic susceptibility for type 2 diabetes in a Chinese population.