The association between thiazolidinediones and hospitalisation for fracture in type 2 diabetic patients: a Taiwanese population-based nested case–control study

摘要

Aims/hypothesis Evidence from the USA has emerged that thiazolidinediones may have a negative effect on the skeleton and increase the risk of fracture, but the association between thiazolidinediones use and fractures has not been evaluated in an Asian population. Using the 2000–2005 Taiwan National Health Insurance claims database, this Taiwanese population-based nested case–control study explored the association between thiazolidinediones use and hospitalisation for bone fracture in type 2 diabetic patients.