Intrauterine Exposure to Diabetes Conveys Risks for Type 2 Diabetes and Obesity A Study of Discordant Sibships

摘要

Intrauterine exposure to diabetes is associated with an excess of diabetes and obesity in the offspring, but the effects of intrauterine exposure are confounded by genetic factors. To determine the role of the intrauter- ine diabetic environment per se, the prevalence of dia- betes and the mean BMI were compared in siblings born before and after their mother was recognized as having diabetes.