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Decontamination and re-use of surgical masks and respirators during the COVID-19 pandemic

机译:在Covid-19流行病中去污和重复使用外科口罩和呼吸器

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Objectives The coronavirus disease 2019 pandemic increased global demand for personal protective equipment (PPE) and resulted in shortages. The study evaluated the re-use of surgical masks and respirators by analysing their performance and safety before and after reprocessing using the following methods: oven, thermal drying, autoclave, and hydrogen peroxide plasma vapour. Methods In total, 45 surgical masks and 69 respirators were decontaminated. Visual integrity, air permeability, burst resistance, pressure differential and particulate filtration efficiency of new and decontaminated surgical masks and respirators were evaluated. In addition, 14 used respirators were analysed after work shifts before and after decontamination using reverse transcription polymerase chain reaction (RT-PCR) and viral culturing. Finally, reprocessed respirators were evaluated by users in terms of functionality and comfort. Results Oven decontamination (75 °C for 45 min) was found to be the simplest decontamination method. Physical and filtration assays indicated that all reprocessing methods were safe after one cycle. Oven decontamination maintained the characteristics of surgical masks and respirators for at least five reprocessing cycles. Viral RNA was detected by RT-PCR in two of the 14 used respirators. Four respirators submitted to viral culture were PCR-negative and culture-negative. Reprocessed respirators used in work shifts were evaluated positively by users, even after three decontamination cycles. Conclusion Oven decontamination is a safe method for reprocessing surgical masks and respirators for at least five cycles, and is feasible in the hospital setting.
机译:目标冠状病毒疾病2019大流行增加了全球对个人防护装备(PPE)的需求,并导致短缺。该研究通过通过以下方法分析了他们的性能和安全性,评估了手术口罩和呼吸器的重复使用:烘箱,热干燥,高压釜和过氧化氢等离子体蒸气。方法总共45种外科口罩和69名呼吸器被净化。评估了新的和净化的外科口罩和呼吸器的视觉完整性,透气性,突发性,压差和颗粒过滤效率。此外,在使用逆转录聚合酶链反应(RT-PCR)和病毒培养后,在去污之前和之后分析了14次使用的呼吸器。最后,通过用户在功能和舒适性方面评估了再加工的呼吸器。结果烘箱净化(75℃45分钟)被发现是最简单的去污方法。物理和过滤测定表明,在一次循环后,所有重新处理方法都是安全的。烤箱去污保持了至少五个再加工循环的外科口罩和呼吸器的特征。通过RT-PCR检测病毒RNA,在14次使用的呼吸器中的两种中检测到。提交给病毒培养的四个呼吸器是PCR阴性和培养阴性。即使在三个去污周期之后,用户也会积极评估工作换档中使用的再加工呼吸器。结论烤箱净化是一种安全的方法,用于再处理手术口罩和呼吸器至少五个循环,并且在医院环境中是可行的。

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