首页> 外文期刊>Neurospine. >Getting Down to the Bare Bones: Does laminoplasty or laminectomy With Fusion Provide Better Outcomes for Patients With Multilevel Cervical Spondylotic Myelopathy?
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Getting Down to the Bare Bones: Does laminoplasty or laminectomy With Fusion Provide Better Outcomes for Patients With Multilevel Cervical Spondylotic Myelopathy?

机译:俯卧到裸体:融合术或融合术治疗多级颈椎病患者提供更好的结果吗?

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Objective Cervical spondylotic myelopathy (CSM) is a degenerative disorder leading to progressive decline in spinal cord function. Cervical laminoplasty (CLP) and cervical laminectomy with fusion (CLF) are standard treatments for multilevel CSM. However, it is still unclear whether one procedure over the other provides better outcomes. Here, we performed a comprehensive review of published articles that compare the clinical outcomes and costs between CLP and CLF for CSM. Methods A literature search was performed using PubMed, Web of Science, and Cochrane databases. Strict exclusion criteria were applied, and included articles were then assessed for publication year, study design, and significant differences in outcome variables. Results From 519 studies identified with search terms, 38 studies were included for the qualitative analysis. Statistically significant differences in the clinical outcomes and costs were found in 18 studies. Eleven studies were prospective or retrospective, and 8 studies were meta-analyses. For the outcome variables of interest, results were reported by classifying into prospective studies, retrospective studies, and meta-analyses. Conclusion CLP and CLF are 2 of the most commonly performed surgical procedures for the treatment of CSM. Although CLP and CLF each provide satisfactory clinical outcomes for patients with CMS, CLP may result in better cervical range of motion and less cost, length of stay, operation time, blood loss, paraspinal muscular atrophy, and rate of nerve palsies as compared to CLF. The major limitation of CLP versus CLF comparison studies includes the heterogeneity in techniques and preoperative criteria. Thus, further validation and investigations in larger cohorts will be required.
机译:目的颈椎椎间盘突出(CSM)是一种退行性疾病,导致脊髓功能逐渐下降。颈椎成形术(CLP)和栓塞(CLF)的宫颈椎板切除术是多级CSM的标准处理。但是,目前尚不清楚对方的一个程序是否提供更好的结果。在这里,我们对公布的文章进行了全面的审查,该文章比较了CSM的CLP和CLF之间的临床结果和成本。方法使用PubMed,Science,Cochrane数据库进行文献搜索。应用严格的排除标准,然后包括出版年份,研究设计以及结果变量的显着差异。结果由搜索条件确定的519项研究,38项研究被包括定性分析。 18项研究中发现了临床结果和成本的统计学意义差异。 11项研究是前瞻性的或回顾性,8项研究是荟萃分析。对于感兴趣的结果变量,通过分类预期研究,回顾性研究和荟萃分析来报告结果。结论CLP和CLF是用于治疗CSM的最常见的手术程序。虽然CLP和CLF每次为CMS患者提供令人满意的临床结果,但CLP可能导致更好的宫颈范围的运动范围和更少的成本,保持长度,操作时间,失血,肩胛骨萎缩,与CLF相比的神经皮肤速度。 CLP与CLF比较研究的主要限制包括技术和术前标准的异质性。因此,将需要进一步验证和较大群组的调查。

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